Periprosthetic Joint Infection Caused by <i>Brucella</i>: Four Case Reports and a Systematic Review of Literature. [PDF]
Wang S +7 more
europepmc +1 more source
Comparative effectiveness of adjunctive rifampicin versus gentamicin for prosthetic valve endocarditis due to <i>Staphylococcus aureus</i>. [PDF]
Kitano T, Yoshida S.
europepmc +1 more source
Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells
ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu +4 more
wiley +1 more source
Therapeutic drug monitoring-guided treatment of XDR TB with an RpoB I491F mutation-a case report. [PDF]
Klingmüller A +12 more
europepmc +1 more source
Abstract Introduction People with tuberculosis‐HIV coinfection face multiple barriers to effective treatment, including social vulnerability, stigma and limited access to healthcare. This study examined factors associated with loss to follow‐up and death among individuals with tuberculosis‐HIV in Brazil.
Lucas Vinícius de Lima +9 more
wiley +1 more source
Method Validation of an Ultra-High-Performance Liquid Chromatography (UHPLC) for the Bioequivalence Study of Rifampicin. [PDF]
Diño AJD +6 more
europepmc +1 more source
Clinical and Postoperative Applications of Manuka Honey in Wound Healing: An Evidence‐Based Review
ABSTRACT Chronic and postoperative wounds remain challenging to manage, with high risks of infection, delayed healing and increased costs. Manuka honey offers antibacterial, anti‐inflammatory, antioxidant and tissue‐regenerative properties through methylglyoxal, phenolic compounds, high sugar content and low pH.
Ayman N. Alhabsi +6 more
wiley +1 more source
We identify the long‐known virulence factor VirJ as a lysyl‐phosphatidylglycerol (L‐PG) hydrolase. Like the chromosomally encoded virulence factor AcvB, it prevents excessive accumulation of L‐PG in the membrane, thereby maintaining efficient T‐DNA transfer via the Type IV secretion system (T4SS) in Agrobacterium tumefaciens.
Britta Lotz +9 more
wiley +1 more source
Clinical characteristics of pregnant patients with rifampicin-resistant tuberculosis: a retrospective analysis. [PDF]
Luo N, Lai M, Tang S, Wu G, Chen H.
europepmc +1 more source
SDE4250 suppressed 26S proteasome activity by targeting CsRPN10 and enhancing its degradation via the proteasome pathway. This impairment of proteasome function subsequently attenuates SA‐mediated defence responses, thereby increasing citrus susceptibility to promote CLas infection.
Yalin Mei +7 more
wiley +1 more source

