Results 261 to 270 of about 191,709 (318)

Bacterial Outer Membrane‐Coated Mesoporous Silica Nanoparticles for Targeted Delivery of Antibiotic Rifampicin against Gram‐Negative Bacterial Infection In Vivo

Advanced Functional Materials, 2021
The efficacy of conventional antibiotics therapeutics has declined rapidly due to the emerged antibiotic resistance. There is an urgent need to develop novel approaches to address the problem of antibiotic shortage, particularly for Gram‐negative ...
Yi Yan Yang
exaly   +2 more sources

Four-Month High-Dose Rifampicin Regimens for Pulmonary Tuberculosis.

NEJM Evidence, 2023
High-Dose Rifampicin Regimen for Pulmonary TuberculosisThis randomized, controlled trial tested the efficacy and safety of high-dose rifampicin (1200 or 1800 mg/d) as part of the treatment regimen for pulmonary tuberculosis.
A. Jindani, D. Atwine, D. Grint, B. Bah, Jack Adams, E. Ticona, B. Shrestha, T. Agizew, S. Hamid, B. Jamil, Adolf Byamukama, Keneth Kananura, I. Mugisha Taremwa, Maryline Bonnet, L. Camara, O. Bah‐sow, K. Bah, N. Bah, M. Sow, César Eduardo Ticona Huaroto, Raquel Mugruza Pineda, Bijesh Tandukar, B. Raya, Neko Shrestha, A. Mathoma, Unami Mathebula-Modongo, J. Basotli, M. Irfan, Dilshad Begum, Ammara Muzammil, I. Ahmed, R. Hasan, M. Burgos, F. Sultan, Maria Hassan, Iqra Masood, C. Robb, J. Decker, S. Grubnic, P. Butcher, A. Witney, J. Dhillon, Tulika Munshi, K. Fielding, T. Harrison   +44 more
semanticscholar   +1 more source

Inhibition of HSPA8 by rifampicin contributes to ferroptosis via enhancing autophagy

Liver international (Print), 2022
Rifampicin is the most common pathogenic factor in anti‐tuberculosis drug‐induced liver injury (AT‐DILI), the mechanisms that it promotes hepatocyte damage in AT‐DILI are not yet to be thoroughly elucidated.
Juan Zhou, Yingzheng Tan, Lingli Hu, Jingli Fu, D. Li, Jun Chen, Y. Long   +6 more
semanticscholar   +1 more source

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes

Nature Microbiology, 2018
Tuberculosis is a significant global health threat, with one-third of the world’s population infected with its causative agent Mycobacterium tuberculosis (Mtb).
Nancy D Marin, Mushtaq Ahmed, Bruce A Rosa   +2 more
exaly   +2 more sources

Rifampicin decreases neuroinflammation to maintain mitochondrial function and calcium homeostasis in rotenone-treated zebrafish

Drug and chemical toxicology (New York, N.Y. 1978), 2020
Among the mechanisms underlying Parkinson’s disease, many pathogenic mechanisms are suggested to be effective such as oxidative stress, mitochondrial dysfunction, disruption of the ubiquitin-proteasome system, and neuroinflammation.
Ilknur Yurtsever, Ü. Üstündağ, İ. Ünal, P. S. Ateş, E. Emekli-Alturfan   +4 more
semanticscholar   +1 more source

An ultra-sensitive "turn-off" fluorescent sensor for the trace detection of rifampicin based on glutathione-stabilized copper nanoclusters.

In Analysis, 2020
Rifampicin is a common antibiotic used in human and veterinary medicine to treat tuberculosis and other diseases caused by numerous pathogenic bacteria. However, the excessive or improper use of rifampicin usually leads to a series of problems, including
Xiao-Man Wu, Jun-Hua Zhang, Zi-Shuo Feng, Wen-Xin Chen, Fei Zhang, Yan Li   +5 more
semanticscholar   +1 more source

RIFAMPICIN

The Lancet, 1969
J M, Murdoch, C F, Speirs, N, Wright, E T, Wallace   +3 more
  +8 more sources