Results 151 to 160 of about 97,638 (260)

Multi‐Omics Analyses Reveal the Red and Far‐Red Light Combination Enhancing Heterologous Protein and Metabolite Production in Nicotiana benthamiana

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Transient expression of exogenous protein in Nicotiana benthamiana leaves via agroinfiltration offers a rapid and efficient platform for functional gene discovery and heterologous production of valuable eukaryotic proteins and metabolites. Though light quality is an important factor for plant photomorphogenesis, its impact on the efficiency of
Yating Zhang   +6 more
wiley   +1 more source

Drug-resistance profile of Mycobacterium tuberculosis to first-line anti-tuberculosis agents in new and previously treated pulmonary tuberculosis patients from Andhra Pradesh, India

open access: yesJournal of Clinical and Scientific Research
Background: Multidrug-resistant tuberculosis (MDR-TB) is a global public health problem. Methods: We tested 104 strains each of Mycobacterium tuberculosis complex (Mtb) isolated from new cases and previously treated cases against four first line anti ...
Anagoni Srikar   +4 more
doaj   +1 more source

Outcomes and safety of concomitant nevirapine and rifampicin treatment under programme conditions in Malawi. [PDF]

open access: yes, 2010
SETTING: Thyolo District Hospital, rural Malawi. OBJECTIVES: To report on 1) clinical, immunological and virological outcomes and 2) safety among human immunodeficiency virus (HIV) infected patients with tuberculosis (TB) who received concurrent ...
Bauerfeind, A   +9 more
core   +1 more source

Household contact management for rifampicin-resistant tuberculosis

open access: yesThe Lancet Global Health, 2022
Anja Reuter   +4 more
openaire   +3 more sources

Engineered Production of Hydroxycinnamoyl Tyramine Conjugates Limits the Growth of the Pathogen Pseudomonas syringae in Arabidopsis

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Hydroxycinnamoyl tyramine conjugates are phenolamides produced by plants in response to pathogen attack and biotic stresses. Their proposed mechanisms of action include cytotoxicity towards pathogens, cell wall reinforcement to restrict pathogen proliferation, and signaling activity to trigger general stress responses.
Halbay Turumtay   +14 more
wiley   +1 more source

Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains

open access: yesInfection and Drug Resistance, 2018
Mallika Lavania,1 Itu Singh,1 Ravindra P Turankar,1 Anuj Kumar Gupta,2 Madhvi Ahuja,1 Vinay Pathak,1 Utpal Sengupta1 1Stanley Browne Laboratory, The Leprosy Mission Trust India, TLM Community Hospital Nand Nagari, 2Agilent Technologies India Pvt Ltd ...
Lavania M   +6 more
doaj  

Antibiotic residues and R-plasmid selection: are in vitro methods good models? [PDF]

open access: yes, 1987
Three clones of E. coli, one of which was harbouring a tetracycline resistance plasmid were inoculated together into the stomach of axenic mice. Without antibiotic selective pressure, the R-Plasmid bearing strain became dominant in the faeces of mice ...
Corpet, Denis E., Lumeau, Solange
core   +2 more sources

Persistent Hyperglycaemia and Transient Dysglycaemia in Tuberculosis: Evaluating the Bidirectional Interaction With Type‐2 Diabetes Mellitus and Clinical Outcomes

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Introduction Poor glycaemic control, indicated by a haemoglobin A1c (HbA1c) level of 7% or higher, increases the risk of active tuberculosis (TB) in patients with diabetes, while active TB can worsen glucose tolerance and insulin resistance, contributing to type‐2 diabetes mellitus (DM) progression.
Augustine Asare Boadu   +11 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor   +4 more
wiley   +1 more source

Stimuli‐Responsive Poly(Disulfide)s: A Versatile Platform for Intelligent Drug Delivery Systems

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
Ring‐opening polymerization based on dynamic disulfide bond exchange is an important method for synthesizing poly(disulfide)s. These polymers possess stimulus‐responsive mechanisms and show broad prospects in intelligent drug delivery. This review systematically discusses the ring‐opening polymerization strategy and research progress of drug delivery ...
Yuechen He   +7 more
wiley   +1 more source

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