Results 201 to 210 of about 2,415,366 (239)

The pattern of rpoB gene mutation of Mycobacterium tuberculosis and predictors of rifampicin resistance detected by GeneXpert MTB/RIF assay in Tanzania. [PDF]

open access: yesPLoS One
Torokaa PR   +12 more
europepmc   +1 more source

Mutations Inside Rifampicin-Resistance Determining Region of rpoB Gene Associated With Rifampicin-Resistance in Mycobacterium tuberculosis

open access: yesJournal of Infection and Public Health, 2018
Rifampicin (RIF) plays a pivotal role in the treatment of tuberculosis due to its bactericidal effects. Because the action of RIF is on rpoB gene encoding RNA polymerase β subunit, 95% of RIF resistant mutations are present in rpoB gene. The majority of the mutations in rpoB gene are found within an 81bp RIF-resistance determining region (RRDR ...
Zaw Lin
exaly   +5 more sources

Detection of Rifampicin-Resistance Mutations in Mycobacterium tuberculosis

open access: yesLancet, The, 1993
Control of tuberculosis is threatened by widespread emergence of drug resistance in Mycobacterium tuberculosis. Understanding the molecular basis of resistance might lead to development of novel rapid methods for diagnosing drug resistance. We set out to determine the molecular basis of resistance to rifampicin, a major component of multidrug regimens ...
T Bodmer, M J Colston, L Matter
exaly   +6 more sources

Acquired Rifampicin Resistance in Thrice-Weekly Antituberculosis Therapy: Impact of HIV and Antiretroviral Therapy.

open access: yesClinical Infectious Diseases, 2014
Risk factors for acquired rifampicin resistance (ARR) among tuberculosis patients on thrice-weekly antituberculosis therapy were baseline isoniazid resistance and HIV.
Soumya Swaminathan   +2 more
exaly   +2 more sources

Acquired resistance to rifampicin by Mycobacterium kansasii

Tubercle, 1976
Two patients with Mycobacterium kansasii infection of the lung had organisms sensitive to rifampicin. Following treatment, essentially with rifampicin alone, the patients began to excrete organisms completely resistant to rifampicin. The ability of M. kansasii to acquire resistance to rifampicin during treatment has been clearly demonstrated.
P T, Davidson, R, Waggoner
openaire   +2 more sources

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