Results 51 to 60 of about 72,471 (294)

Pseudomonas aeruginosa bacteremia in patients undergoing liver transplantation: An emerging problem [PDF]

open access: yes, 1991
In our institution, Pseudomonas aeruginosa bacteremia appeared to occur with increasing frequency in patients undergoing liver transplantation. We thus conducted a prospective study to define risk factors and outcome in these patients.
Korvick, JA   +3 more
core  

Intracranial tuberculous mass lesions treated with thalidomide in an immunocompetent child from a low tuberculosis endemic country: A case report [PDF]

open access: yes, 2018
Rationale: Tuberculous meningitis is a highly morbid, often fatal disease. Patient concern: We describe a case of an Italian child. Diagnoses: we diagnosed early a Tuberculous meningitis complicated by the occurrence of hydrocephalus, stroke, and ...
Ajassa, Camilla   +8 more
core   +1 more source

Genomic Insights Into a Strong Biofilm‐Forming Enterococcus faecalis MTR_EFS01 Strain Isolated From a Shrimp in Bangladesh

open access: yesAnimal Research and One Health, EarlyView.
This study characterizes a multidrug‐resistant and strong biofilm‐forming Enterococcus faecalis strain obtained from a shrimp sample in Bangladesh. ABSTRACT Enterococcus faecalis is known for its ability to form strong biofilms and its role as an opportunistic pathogen. In this study, we screened and characterized a multidrug‐resistant (MDR) and strong
Md. Ashek Ullah   +4 more
wiley   +1 more source

Antimicrobial effects of folk medicinal plants from the North of Iran against Mycobacterium tuberculosis [PDF]

open access: yes, 2015
Background: Medicinal plants have been used traditionally in Golestan province (north of Iran), against Mycobacterium tuberculosis or the clinical signs of tuberculosis (TB).
Davoodi, H.   +6 more
core  

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]

open access: yes, 2019
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon   +9 more
core   +2 more sources

Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen   +6 more
wiley   +1 more source

Rifampin pharmacokinetics in children, with and without human immunodeficiency virus infection, hospitalized for the management of severe forms of tuberculosis

open access: yesBMC Medicine, 2009
Background Rifampin is a key drug in antituberculosis chemotherapy because it rapidly kills the majority of bacilli in tuberculosis lesions, prevents relapse and thus enables 6-month short-course chemotherapy.
McIlleron Helen   +8 more
doaj   +1 more source

Detection of genomic mutations in katG and rpoB genes among multidrug-resistant Mycobacterium tuberculosis isolates from Tehran, Iran

open access: yesNew Microbes and New Infections, 2021
Multidrug-resistant (MDR) Mycobacterium tuberculosis strains, defined as resistant to at least isoniazid and rifampin, have emerged as a major worldwide health threat. Spontaneous point mutations in various genes of M.
B. Motavaf   +5 more
doaj   +1 more source

Enhanced Vatiquinone Bioavailability With Fatty Meals and Optimal Dosing Schedule

open access: yesBiopharmaceutics &Drug Disposition, EarlyView.
This investigation discusses two clinical studies. One investigated the effect of fatty meals (≥ 25% fat) on vatiquinone PK exposures, and the other one characterized vatiquinone PK profiles when administered on a TID dosing regimen corresponding to mealtimes. The data support the recommendation of administering vatiquinone with fatty meals (≥ 25% fat)
Lucy Lee   +6 more
wiley   +1 more source

Transcriptional Approach for Decoding the Mechanism of rpoC Compensatory Mutations for the Fitness Cost in Rifampicin-Resistant Mycobacterium tuberculosis

open access: yesFrontiers in Microbiology, 2018
Multidrug-resistant tuberculosis (TB), defined as TB resistant to the two first-line drugs, isoniazid and rifampin, is a serious challenge to global TB eradication efforts.
Zhihong Xu   +9 more
doaj   +1 more source

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