Scientific Reports, 2022 Milvexian (BMS-986177/JNJ-70033093) is a potent, oral small molecule that inhibits the active form of factor XI with high affinity and selectivity.
Vidya Perera +8 more
doaj +1 more source
Genome-Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters. [PDF]
, 2019 Bacteria express numerous efflux transporters that confer resistance to diverse toxicants present in their environment. Due to a high level of functional redundancy of these transporters, it is difficult to identify those that are of most importance in ...
Deutschbauer, Adam M +4 more
core +1 more source
Efficacy of Three-Week Oxytetracycline or Rifampin Monotherapy Compared with a Combination Regimen against the Filarial Nematode Onchocerca ochengi [PDF]
, 2014 Onchocerciasis (river blindness), caused by the filarial nematode Onchocerca volvulus, is a major cause of visual impairment and dermatitis in sub-Saharan Africa. As O.
Bah, Germanus S +5 more
core +1 more source
Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial. [PDF]
, 2020 BACKGROUND: Buruli ulcer is a neglected tropical disease caused by Mycobacterium ulcerans infection that damages the skin and subcutis. It is most prevalent in western and central Africa and Australia.
Abass, KM +31 more
core +3 more sources
Antimicrobial Agents and Chemotherapy, 2018 Rifampin has been used as an agent in combination therapy in orthopedic device-related infections (ODRI) for almost three decades. The aim of this review is to provide data regarding the role of rifampin against biofilm infection in vitro, in animal ...
W. Zimmerli, P. Sendi
semanticscholar +1 more source
In-vitro evaluation of different antimicrobial combinations with and without colistin against carbapenem-resistant acinetobacter baumannii [PDF]
, 2019 Carbapenem-resistant Acinetobacter baumannii (CR-Ab) infections are associated with high morbidity and mortality. The aim of the study was to evaluate the in-vitro activity of different antimicrobial combinations (with and without colistin, COL) against ...
De Angelis, Massimiliano +6 more
core +1 more source
Safety and Side Effects of Rifampin versus Isoniazid in Children
New England Journal of Medicine, 2018 BACKGROUND The treatment of latent infection with Mycobacterium tuberculosis is important in children because of their vulnerability to life‐threatening forms of tuberculosis disease.
T. Diallo +20 more
semanticscholar +1 more source
Canadian Journal of Infectious Diseases and Medical Microbiology, 2006 A case of presumed bacillus Calmette-Guérin (BCG) cystitis in an elderly female patient following direct intravesical BCG instillation treatment for papillary transitional cell carcinoma is reported.
Joyce N Wolfe +3 more
doaj +1 more source
Penicillin Use in Meningococcal Disease Management: Active Bacterial Core Surveillance Sites, 2009. [PDF]
, 2016 In 2009, in the Active Bacterial Core surveillance sites, penicillin was not commonly used to treat meningococcal disease. This is likely because of inconsistent availability of antimicrobial susceptibility testing and ease of use of third-generation ...
Anderson, Raydel +18 more
core +2 more sources
Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis [PDF]
, 2015 Supported by the Global Alliance for TB Drug Development with support from the Bill and Melinda Gates Foundation, the European and Developing Countries Clinical Trials Partnership, U.S. Agency for International Development, U.K.
Crook, Angela M. +9 more
core +1 more source