Results 51 to 60 of about 48,908 (228)

Influence of Single Nucleotide Polymorphisms on Rifampin Pharmacokinetics in Tuberculosis Patients

Antibiotics, 2020
Rifampin (RF) is metabolized in the liver into an active metabolite 25-desacetylrifampin and excreted almost equally via biliary and renal routes. Various influx and efflux transporters influence RF disposition during hepatic uptake and biliary excretion.
Levin Thomas, Sonal Sekhar Miraj, Mallayasamy Surulivelrajan, Muralidhar Varma, Chidananda S. V. Sanju, Mahadev Rao   +5 more
doaj   +1 more source

Factors Associated with Variability in Rifampin Plasma Pharmacokinetics and the Relationship between Rifampin Concentrations and Induction of Efavirenz Clearance

, 2014
Study Objectives To identify factors associated with variability in rifampin plasma pharmacokinetics and explore the relationship between rifampin pharmacokinetics and change in efavirenz plasma pharmacokinetics with rifampin coadministration. Methods In
Behrang D. Mahjoub, Cao, Lei, Court, Michael H, Mahjoub, Behrang D, Charles A. Peloquin, Yang, Hongmei, Lei Cao, Poethke, Pamela, Kwara, Awewura, Michael H. Court, Peloquin, Charles A, Pamela Poethke, Karen T. Tashima, Tashima, Karen T, Jaclynn Kurpewski, Awewura Kwara, Hongmei Yang, Kurpewski, Jaclynn   +17 more
core   +1 more source

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

Rheumatology &Autoimmunity, EarlyView.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu, Ming Zheng, Danny Arias, Andreina M. Paulino, Aisha Niaz, James Devlin, Valentin Marian   +6 more
wiley   +1 more source

Mycobacterial SigA and SigB Cotranscribe Essential Housekeeping Genes during Exponential Growth

mBio, 2019
Mycobacterial σB belongs to the group II family of sigma factors, which are widely considered to transcribe genes required for stationary-phase survival and the response to stress.
Kelley Hurst-Hess, Rajesh Biswas, Yong Yang, Paulami Rudra, Erica Lasek-Nesselquist, Pallavi Ghosh   +5 more
doaj   +1 more source

TB = Tuberculosis, RS-TB = rifampin sensitive M. tuberculosis, RR-TB = rifampin resistant M. tuberculosis.

, 2013
6 of 12 patients who had rifampin resistant M. tuberculosis at initial tuberculosis diagnosis, re-cultured rifampin resistant M. tuberculosis at clinical deterioration. i.e. 29 new cases of rifampin resistant M.
Graeme Meintjes (221054), Chelsea Morroni (374326), Dominique J. Pepper (221049), Robert J. Wilkinson (130050), Kevin Rebe (374325)   +4 more
core   +1 more source

Doses of rifampin by weight band.

, 2023
Doses of rifampin by weight band.
Victoria Cook (14559272), Dina Fisher (574945), Richard Long (105563), Greg J. Fox (7022687), Rovina Ruslami (6324572), Thu Anh Nguyen (10734756), Leila Barss (6598055), James Johnston (2008615), Dick Menzies (66118), Federica Fregonese (442412), Andrea Benedetti (139371), Lika Apriani (12175822), Viet Nhung Nguyen (3213090)   +12 more
core   +1 more source

Mechanistic insights into HapC: A key enzyme in prodiginine biosynthesis in Hahella chejuensis

The FEBS Journal, EarlyView.
HapC catalyzes prodiginine biosynthesis through coordinated movements of its ATP‐binding, substrate‐binding, and catalytic‐swivel domains. The enzyme shows tolerance toward short‐chain MAP analogs, and docking analyses reveal key residues and structural features underlying its substrate flexibility.
Yueh‐Te Chan, Aden Dhana Rizkita, Hsin‐Ju Hsieh, Shu‐Fang Hsu, Tony Eight Lin, Wei‐Jan Huang, Kai‐Cheng Hsu, Sheila Nathan, Peiching Chang, Andrew H.‐J. Wang, Cheng‐Chung Lee   +10 more
wiley   +1 more source

Reassessment of the genetic basis of natural rifampin resistance in the genus Rickettsia

MicrobiologyOpen
Rickettsia, a genus of obligate intracellular bacteria, includes species that cause significant human diseases. This study challenges previous claims that the Leucine‐973 residue in the RNA polymerase beta subunit is the primary determinant of rifampin ...
Julien Amoros, Noor Fattar, Marie Buysse, Meriem Louni, Joanne Bertaux, Didier Bouchon, Olivier Duron   +6 more
doaj   +1 more source

Rifampin-loaded Mesoporous Silica Nanoparticles Improved Physical and Mechanical Properties and Biological Response of Acrylic Bone Cement

Journal of Medical Signals and Sensors
Background: Acrylic bone cement, which is used to fix implants in the knee and hip, is prone to contamination with various types of infections. Adding small amounts of different antibiotics to the cement can help prevent and treat infections.
Mohammad Reza Shafiei, Nader Nezafati, Saeed Karbasi, Anousheh Zargar Kharazi   +3 more
doaj   +1 more source

Rifampin (INN Rifampicin) [PDF]

Journal of Pain and Symptom Management, 2015
Therapeutic Reviews aim to provide essential independent information for health professionals about drugs used in palliative and hospice care. Additional content is available on www.palliativedrugs.com. Country-specific books (Hospice and Palliative Care Formulary USA, and Palliative Care Formulary, British and Canadian editions) are also available and
Paul, Howard, Robert, Twycross, Graham, Grove, Sarah, Charlesworth, Mary, Mihalyo, Andrew, Wilcock   +5 more
openaire   +2 more sources