Results 111 to 120 of about 6,040 (212)

Rimonabant Precipitates Anxiety in Rats Withdrawn from Palatable Food: Role of the Central Amygdala

, 2013
The anti-obesity medication rimonabant, an antagonist of cannabinoid type-1 (CB1) receptor, was withdrawn from the market because of adverse psychiatric side effects, including a negative affective state. We investigated whether rimonabant precipitates a
Valentina Sabino, A. Iemolo, E. P. Zorrilla, Pierangelo Orlando, P. Orlando, A. Blasio, STEARDO, LUCA, S. Petrosino, Angelo Blasio, F. A. Iannotti, Vincenzo Di Marzo, K. C. Rice, P. Cottone, Attilio Iemolo, Pietro Cottone, Luca Steardo, Stefania Petrosino, Kenner C Rice, Fabio Arturo Iannotti, V. Di Marzo, Eric P Zorrilla, V. Sabino   +21 more
core   +1 more source

Rimonabant (acomplia®), obésité et diabiète de type 2

, 2008
Le rimonabant (Acomplia®) est une molécule au mécanisme d'action original, antagoniste du récepteur CB1 du système endocannabinoïde qui joue un rôle majeur dans la régulation de l'équilibre énergétique du corps.
BESSIERES, Hélène, HANAIRE-BROUTIN, Hélène   +1 more
core  

Rimonabant 2-methoxyethanol solvate and method for preparing same

, 2007
The invention relates to a rimonabant 2-methoxyethanol solvate, and to a method for preparing the same ...
Coquerel, Gérard, Fours, Baptiste
core  

Involvement of CB1 cannabinoid receptors in methamphetamine-related decision-making and social behavior deficits. [PDF]

BMC Neurosci
Mousavi T, Hatami N, Niknamfar S, Naseri M, Rafaiee R, Tamijani SMS, Ranaiy MS, Ghazvini H.   +7 more
europepmc   +1 more source

Discrete Choice Experiment (DCE) as a Tool to Elicit Patient Preferences in a Complex Benefit-Risk Evaluation: A Case Study. [PDF]

Clin Drug Investig
E JY, Mt-Isa S, Hockley K, Zhu K, Tcherny-Lessenot S, Juhaeri J.   +5 more
europepmc   +1 more source

Rimonabant n,n-dimethylformamide solvate, and method for preparing same

, 2007
The invention relates to a rimonabant N,N-dimethylformamide solvate, and to a method for preparing the ...
Coquerel, Gérard, Fours, Baptiste
core  

Cannabinoid 1 receptor occupancy and neurovascular responses induced by agonist, antagonist/inverse-agonist and potential modulator in non-human primate brains: PET/fMRI study. [PDF]

J Cereb Blood Flow Metab
Yoo CH, Xu Y, Bagdasarian FA, Lin YS, Wang C, Wey HY.   +5 more
europepmc   +1 more source

Are endocannabinoid type 1 receptor gene (CNR1) polymorphisms associated with obesity and metabolic syndrome in postmenopausal Polish women?

, 2009
Objective: The aim of this study was to determine whether genetic variation at the cannabinoid receptor-1 (CNR1) locus could have an effect on adiposity, fat distribution and obesity-related metabolic disorders in Polish postmenopausal women.Design and ...
Felicja Lwow, Diana Jedrzejuk, Lukasz Laczmanski, Andrzej Milewicz, Katarzyna Dunajska, Urszula Tworowska-Bardzinska   +5 more
core  

Melatonin mitigates hormonal toxicity in cannabis-treated female Wistar rats: involvement of cannabinoid receptor. [PDF]

J Cannabis Res
Oluwasola A.
europepmc   +1 more source

Short Communication: The Peripheral Cannabinoid CB₁ Receptor Antagonist AM6545 Modifies Cardiovascular Effects of Endocannabinoids in DOCA-Salt Rats. [PDF]

Int J Mol Sci
Remiszewski P, Schlicker E, Grzęda E, Weresa J, Toczek M, Malinowska B.   +5 more
europepmc   +1 more source