Results 111 to 120 of about 6,428 (208)

Rimonabant (acomplia®), obésité et diabiète de type 2

, 2008
Le rimonabant (Acomplia®) est une molécule au mécanisme d'action original, antagoniste du récepteur CB1 du système endocannabinoïde qui joue un rôle majeur dans la régulation de l'équilibre énergétique du corps.
BESSIERES, Hélène, HANAIRE-BROUTIN, Hélène   +1 more
core  

Discrete Choice Experiment (DCE) as a Tool to Elicit Patient Preferences in a Complex Benefit-Risk Evaluation: A Case Study. [PDF]

Clin Drug Investig
E JY, Mt-Isa S, Hockley K, Zhu K, Tcherny-Lessenot S, Juhaeri J.   +5 more
europepmc   +1 more source

Modulating the endocannabinoid system in alcohol use disorder: A translational systematic review and meta-analysis of preclinical and human studies. [PDF]

Mol Psychiatry
Costa GPA, Cerezo-Matias MA, Funaro MC, Bagdas D, Kaye A, Krystal J, Petrakis I, De Aquino JP.   +7 more
europepmc   +1 more source

Rimonabant n,n-dimethylformamide solvate, and method for preparing same

, 2007
The invention relates to a rimonabant N,N-dimethylformamide solvate, and to a method for preparing the ...
Coquerel, Gérard, Fours, Baptiste
core  

Cannabinoid 1 receptor occupancy and neurovascular responses induced by agonist, antagonist/inverse-agonist and potential modulator in non-human primate brains: PET/fMRI study. [PDF]

J Cereb Blood Flow Metab
Yoo CH, Xu Y, Bagdasarian FA, Lin YS, Wang C, Wey HY.   +5 more
europepmc   +1 more source

Glucocorticoid-endocannabinoid crosstalk in the ventrolateral periaqueductal gray (vlPAG) promotes pain resolution. [PDF]

Neuropsychopharmacology
Coutens B, Bouchet CA, Gvon I, Patti LC, De Anda Gamboa CM, Jewett DC, Klawitter J, Klawitter J, Heinricher MM, Ingram SL.   +9 more
europepmc   +1 more source

Minor cannabinoids CBD, CBG, CBN, and CBC differentially modulate sensory neuron activation. [PDF]

J Pharmacol Exp Ther
Rabl K, Gruenke L, Banfal A, Eilers H, Hellman J, Schumacher MA.   +5 more
europepmc   +1 more source

Melatonin mitigates hormonal toxicity in cannabis-treated female Wistar rats: involvement of cannabinoid receptor. [PDF]

J Cannabis Res
Oluwasola A.
europepmc   +1 more source

Targeting dysregulated CB1 receptors in a Down syndrome mouse model improves neurological outcomes. [PDF]

Alzheimers Dement
Vázquez-Oliver A, Pérez-García S, Romero-Pérez R, Pizarro N, Galarraga-Shinin D, Molina-Porcel L, de la Torre R, Maldonado R, Ozaita A.   +8 more
europepmc   +1 more source

Short Communication: The Peripheral Cannabinoid CB₁ Receptor Antagonist AM6545 Modifies Cardiovascular Effects of Endocannabinoids in DOCA-Salt Rats. [PDF]

Int J Mol Sci
Remiszewski P, Schlicker E, Grzęda E, Weresa J, Toczek M, Malinowska B.   +5 more
europepmc   +1 more source