Results 101 to 110 of about 6,040 (212)
Antihyperlipidemic and Antiatherosclerotic Activity of Rimonabant in Wistar albino Rats
, 2020 The present study was carried out to investigate antihyperlipidemic and antiatherosclerotic effect of rimonabant against hyperlipidemia induced by high fat diet in wistar albino rats. Wistar albino rats were divided in 6 groups of 6 rats in each.
Ashish Mahajan, Praful Patel, Patil Sd
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Efficacy and safety of rimonabant for improvement of multiple cardiometabolic risk factors in overweight/obese patients: pooled 1-year data from the Rimonabant in Obesity (RIO) program. [PDF]
, 2008 peer reviewedOBJECTIVE: To better define the efficacy and safety of rimonabant, the first selective cannabinoid type 1 (CB(1)) receptor antagonist, in a large population of overweight and obese patients using pooled efficacy data from three Phase III ...
Despres, Jean-Pierre +4 more
core +1 more source
Journal of Analytical Methods in Chemistry, 2012 A simple, accurate, and precise HPLC method was developed and validated for determination of rimonabant in human plasma. Following liquid-liquid extraction, chromatographic separation was accomplished using C18 column with mobile phase consisting of ...
Shravan Bankey +5 more
doaj +1 more source
Risk of Depressive Episodes with Rimonabant
, 2011 Background: Marketing authorization for rimonabant was withdrawn in October 2008, mainly because the psychiatric adverse effects could not be addressed by further risk minimization.Objective: The aim of the study was to compare the risk of major and ...
Lynda Wilton +7 more
core +1 more source
Rimonabant and synthesis of its 4-methylaminoderivative
, 2013 Předkládaná práce se zabývá vlastnostmi a syntézou účinné látky s triviálním názvem rimonabant, která byla v minulosti intenzivně studována především v souvislosti s léčbou obezity.
Kratochvílová, Eliška
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, 2009 BACKGROUND: Emotional processing measures are sensitive to acute administration of clinically useful antidepressant drugs. We wished to test the hypothesis that these models would also be able to detect agents likely to cause depression as an adverse ...
Horder, J +6 more
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Cannabinoid CB(1) receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats
, 2011 Exposure to cues previously associated with drug intake leads to relapse by activating previously acquired memories. Based on previous findings, in which cannabinoid CB(1) receptors were found to be critically involved in specific aspects of learning and
Wang, Ji-Shi +15 more
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Synergetic Insulin Sensitizing Effect of Rimonabant and BGP-15 in Zucker-Obes Rats
, 2013 Abdominal obesity is referred for as a common pathogenic root of multiple risk factors, which include insulin resistance, dyslipidemia, hypertension, and a pro-atherogenic and pro- inflammatory state.
Vígh, László Jr. +9 more
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Modulation zentraler Sensibilisierungsvorgänge durch den selektiven CB1-Antagonisten Rimonabant
, 2012 1 Background The application of cannabinoid agonists as analgesics in patients with neuropathic pain is currently a well-argued subject. Central sensitization due to chronic painful stimulation is thought to be an important factor in the pathogenesis of ...
Bürgel, Anna-Lena
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