Results 91 to 100 of about 853,691 (310)

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Determining Inversion Barriers in Atrop- isomers – A Tutorial for Organic Chemists

open access: yesCHIMIA, 2016
Dynamic behavior is a fascinating property of natural and artificial systems and its understanding has significantly impacted the transformation of molecular interchanges into controlled molecular motion. In this tutorial, the key descriptors of
Michel Rickhaus   +2 more
doaj   +1 more source

Detecting Majorana modes through Josephson junction ring-quantum dot hybrid architectures [PDF]

open access: yes, 2017
Unequivocal signatures of Majorana zero energy modes in condensed matter systems and manipulation of the associated electron parity states are highly sought after for fundamental reasons as well as for the prospect of topological quantum computing.
arxiv   +1 more source

A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants [PDF]

open access: yes, 2008
Background: The advent of combinatorial chemistry has revived the interest in five-membered heterocyclic rings as scaffolds in pharmaceutical research. They are also the target of modifications in nucleic acid chemistry.
Hendrickx, Pieter, Martins, José
core   +4 more sources

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Thermo-Acidic Pretreatment of Beach Macroalgae from Rügen to Optimize Biomethane Production—Double Benefit with Simultaneous Bioenergy Production and Improvement of Local Beach and Waste Management

open access: yesMarine Drugs, 2015
Eutrophication is a phenomenon which can rapidly generate masses of marine macroalgae, particularly in areas with high nutrient pollution. Washed ashore, this biomass impairs coastal tourism and negatively affects the coastal ecosystem. The present study
Yann Nicolas Barbot   +2 more
doaj   +1 more source

Impact of Solvent Treatment of the Superionic Argyrodite Li6PS5Cl on Solid‐State Battery Performance

open access: yesAdvanced Energy & Sustainability Research, 2021
With growing interest in solution‐based processing of electrolytes for all‐solid‐state batteries comes the need to more deeply understand potential detrimental effects of the solvent on electrolyte materials, as well as effects on the cell performance ...
Justine Ruhl   +3 more
doaj   +1 more source

An Electronically Non-Adiabatic Generalization of Ring Polymer Molecular Dynamics [PDF]

open access: yesarXiv, 2013
In this thesis I generalize Ring Polymer Molecular Dynamics (RPMD) rate theory to electronically non-adiabatic systems, followed by application to two one-dimensional curve crossing models and a multidimensional spin-boson model.
arxiv  

On the importance of disc chemistry in the formation of protoplanetary disc rings [PDF]

open access: yesarXiv, 2023
Radial substructures have now been observed in a wide range of protoplanetary discs (PPDs), from young to old systems, however their formation is still an area of vigorous debate. Recent magnetohydrodynamic (MHD) simulations have shown that rings and gaps can form naturally in PPDs when non-ideal MHD effects are included.
arxiv  

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