Hydrogen bonding networks and cooperativity effects in the aqueous solvation of trimethylene oxide and sulfide rings by microwave spectroscopy and computational chemistry [PDF]
, 2021 Weslley G. D. P. Silva +1 more
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Spatially Resolved Chemistry in Nearby Galaxies II. The Nuclear Bar in Maffei 2
, 2012 We present 2" - 10" imaging of eleven transitions from nine molecular species across the nuclear bar in Maffei 2. The data were obtained with the BIMA and OVRO interferometers. The ten detected transitions are compared with existing CO isotopologues, HCN,
Meier, David S., Turner, Jean L.
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Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Secondary 3‐Chloropiperidines: Powerful Alkylating Agents
ChemistryOpenIn previous works, we demonstrated that tertiary 3‐chloropiperidines are potent chemotherapeutics, alkylating the DNA through the formation of bicyclic aziridinium ions. Herein, we report the synthesis of novel secondary 3‐chloropiperidine analogues. The
Mats Georg +5 more
doaj +1 more source
Coordination chemistry of perhalogenated cyclopentadienes and alkynes XIV. Synthesis of dinuclear ring-bridged cymantrenes with SiMe2 or TiCp2 bridges. Structures of [(OC)3Mn(C5Br4−)]2SiMe2 and [(OC)3Mn(C5Cl4−)]2TiCp2 [PDF]
, 1994 Karlheinz Sünkel +2 more
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Types and properties of metal-free catalysts for living polymerizations of biomaterials [PDF]
, 2008 Syntéza biokompatibilních a biodegradabilních polyesterů, použitelných převážně v medicíně, využívá pro polymeraci za otevření kruhu katalyzátory na bázi kovu (např. Sn, Al atd.), které se mohou po implantaci deponovat v těle.
Repka, Martin
core
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Conclusions and recommendations: Exploration of the Saturn system [PDF]
Saturn missions have the following principal goals, in order of importance: (1) Intensive investigation of the atmosphere of Saturn; (2) determination of regional surface chemistry and properties of the surface features of satellites and properties of ...
Hunten, D. M.
core +1 more source