FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
DDQ-promoted synthesis of 2-benzoylbenzofurans and benzofuro[2,3-<i>c</i>]pyridines using 2'-hydroxy ethyl cinnamate and phenacyl bromides. [PDF]
RSC AdvSaini SM +3 more
europepmc +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
FEBS Open Bio, EarlyView.Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Beyond Wittig Olefination: Phosphorus Ylide as a Ring-Expansion Reagent for Dibenzocycloheptanone Synthesis. [PDF]
JACS AuLi L, Zha H, Xue X, Duan L, Gu Z.
europepmc +1 more source
THE INFLUENCE OF RING MOSS BOG ON VARIABILITY OF WATER CHEMISTRY OF SMALL HUMIC LAKES
, 2007 Tomasz Joniak +2 more
openalex +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Total syntheses of highly oxidative <i>Ryania</i> diterpenoids facilitated by innovations in synthetic strategies. [PDF]
Beilstein J Org ChemCao ZQ, Qiao JB, Zhao YM.
europepmc +1 more source
Synthesis and characterization of block-graft terpolymer by reversible addition/fragmentation chain transfer and ring-opening polymerization and grafting to "click" chemistry [PDF]
Melahat Göktaş, Cengiz Aykaç
openalex +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source