Results 61 to 70 of about 830,676 (348)

Acid-catalyzed ring-opening reactions of a cyclopropanated 3-aza-2-oxabicyclo[2.2.1]hept-5-ene with alcohols

Beilstein Journal of Organic Chemistry, 2017
The acid-catalyzed ring-opening reactions of a cyclopropanated 3-aza-2-oxabicylic alkene using alcohol nucleophiles were investigated. Although this acid-catalyzed ring-opening reaction did not cleave the cyclopropane unit as planned, this represent the ...
Katrina Tait, Alysia Horvath, Nicolas Blanchard, William Tam   +3 more
doaj   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim, Natalie Bradford, David Brain, Sameera Senanayake, Sanjeewa Kularatna, Kate Young, Christine Cashion, Tim Hassall, Susanna Cramb   +8 more
wiley   +1 more source

Tandem ring‐opening–ring‐closing metathesis for functional metathesis catalysts [PDF]

, 2016
Use of a tandem ring-opening–ring-closing metathesis (RORCM) strategy for the synthesis of functional metathesis catalysts is reported. Ring opening of 7-substituted norbornenes and subsequent ring-closing metathesis forming a thermodynamically stable
Ambade, Bielawski, Bielawski, Bielawski, Buchmeiser, Burtscher, Calderon, Gestwicki, Hanik, Hilf, Hilf, Hilf, Holtsclaw, Ivin, Katayama, Katayama, Kolonko, Kress, La, Lane, Lee, Lexer, Lummiss, Matson, Nagarkar, Nagarkar, Nagarkar, Owen, Park, Park, Pietraszuk, Pietraszuk, Quignard, Rybak, Schrock, Schwab, Weatherhead, Zuercher   +37 more
core   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

One-Pot Access to Functionalised Malamides via Organocatalytic Enantioselective Formation of Spirocyclic β-Lactone-Oxindoles and Double Ring-Opening

Molecules
Malamides (diamide derivatives of malic acid) are prevalent in nature and of significant biological interest, yet only limited synthetic methods to access functionalised enantiopure derivatives have been established to date.
Alastair J. Nimmo, Kevin Kasten, George White, Julia Roeterdink, Aidan P. McKay, David B. Cordes, Andrew David Smith   +6 more
doaj   +1 more source

A Tandem Approach to Photoactivated Olefin Metathesis: Combining a Photoacid Generator with an Acid Activated Catalyst [PDF]

, 2009
Combining an acid activated precatalyst with a photoacid generator (PAG) in the presence of ultraviolet light resulted in a highly efficient catalyst for olefin metathesis.
Grubbs, Robert H., Keitz, Benjamin K.
core   +1 more source

Deletion of cytosolic gating ring decreases gate and voltage sensor coupling in BK channels [PDF]

, 2017
Large conductance Ca(2+)-activated K(+) channels (BK channels) gate open in response to both membrane voltage and intracellular Ca(2+). The channel is formed by a central pore-gate domain (PGD), which spans the membrane, plus transmembrane voltage ...
Adams, Adelman, Alvarez, Atkinson, Bao, Bao, Barrett, Behrens, Braun, Brayden, Brelidze, Brelidze, Budelli, Butler, Cox, Cui, Cui, Ferguson, Guohui Zhang, Hite, Hite, Horrigan, Horrigan, Hu, Hudspeth, Hudspeth, Jianmin Cui, Jingyi Shi, Karl L. Magleby, Kelli McFarland, Lancaster, Latorre, Lawrence Salkoff, Lee, Lee, Li, Lingle, Long, Marty, Meera, Meera, Meredith, Nimigean, Niu, Orio, Pallotta, Petersen, Robitaille, Rothberg, Schreiber, Shen, Shi, Silberberg, Sun, Sweet, Tao, Tseng-Crank, Wallner, Wei, Wellman, Wu, Wu, Xia, Xia, Xia, Yakang Jin, Yang, Yang, Yang, Yang, Yanyan Geng, Yuan, Yuan, Zhang, Zhang   +74 more
core   +3 more sources

Inpatient Food Insecurity and Pediatric Hematology Oncology Hospitalization Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Children with cancer and blood disorders are at risk for food insecurity (FI). We aimed to describe the association of inpatient food insecurity (IFI) and hospitalization outcomes among patients admitted to the pediatric hematology oncology service. Of 325 caregivers screened for IFI, 60 (18.6%) screened positive.
Joanna M. Robles, Greg Russell, Leila H. DeWitt, Kimberly Montez, Callie L. Brown   +4 more
wiley   +1 more source

Unexplored Nucleophilic Ring Opening of Aziridines

Molecules, 2010
The reactivity of dianions of carboxylic acids towards aziridines has been studied. Although, a similar reactivity to that of enolates from ketones, esters or amides has been observed, the method directly yields g-aminoacids in one step.
Ana María Costero, Salvador Gil, Margarita Parra, Pablo Rodríguez   +3 more
doaj  

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source