Results 71 to 80 of about 1,369,818 (304)

Enantioselective cyanation via radical-mediated C–C single bond cleavage for synthesis of chiral dinitriles

Nature Communications, 2019
Ring-opening reaction via selective cleavage of C–C bond is a powerful strategy to increase molecular complexity. Here the authors present the facile synthesis of chiral 1,5- and 1,6-dinitriles via the radical-mediated ring-opening and enantioselective ...
Tao Wang, Yi-Ning Wang, Rui Wang, Bo-Chao Zhang, Chi Yang, Yan-Lin Li, Xi-Sheng Wang   +6 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Cationic-anionic synchronous ring-opening polymerization

Nature Communications
Chemical reactions with incompatible mechanisms (such as nucleophilic reactions and electrophilic reactions, cationic polymerization and anionic polymerization) are usually difficult to perform simultaneously in one-pot.
Wenli Wang, Xue Liang, Hengxu Liu, Jiamin Zhang, Yuanzu Zhang, Beibei Zhang, Jianhua Li, Yunqing Zhu, Jianzhong Du   +8 more
doaj   +1 more source

Ring-Opening Metathesis of a Cyclic Imine

, 2016
Pyrroline, a five-membered cyclic imine, undergoes ring-opening metathesis with alkylidene complexes of the class Mo(CHR‘)(NAr)(OR)2 (Ar = 2,6 diisopropylphenyl; R = CMe3, CMe2(CF3), CMe(CF3)2; R‘ = CMe3, CPhMe2).
Steven J. Geib (1328757), Tara Y. Meyer (1532398), Gidget K. Cantrell (3076827)   +2 more
core   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Ring-Opening Olefin Metathesis of Twisted Amides: Activation of Amide Bonds by CC Cleavage

, 2019
Selective CC bond cleavage in twisted amides by ring-opening olefin metathesis (ROM) was accomplished. The reaction represents the third mechanism for ring opening of nonplanar amide bonds discovered.
Roger Lalancette, Michal Szostak, Michal Szostak (1305681), Roman Szostak, Qun Zhao (603175), Qun Zhao, Roman Szostak (1545610), Roger Lalancette (1581853)   +7 more
core   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Ring-Opening Protonolysis of Strained Silicon-Containing Rings:  A New Approach to Ions with Silylium Character

, 2016
Ring-Opening Protonolysis of Strained Silicon-Containing Rings:  A New Approach to Ions with Silylium ...
Alan J. Lough (1306146), Ian Manners (1314384), Mark J. MacLachlan (1263879), Sara C. Bourke (3008637)   +3 more
core   +2 more sources

Selective Synthesis of Tetrahydroisoquinoline and Piperidine Scaffolds by Oxidative Ring Opening/Ring Closing Protocols of Substituted Indenes and Cyclopentenes

ChemistryOpen
Novel tetrahydroisoquinoline and piperidine derivatives were selectively synthesized from substituted indenes or cyclopentenes. The process starts with an oxidative cleavage of the ring olefin bond, which gives reactive diformyl intermediates.
Anas Semghouli, László Drahos, Jianlin Han, Loránd Kiss, Melinda Nonn   +4 more
doaj   +1 more source

Synthesis of Enantiomerically Pure N-Boc-Protected 1,2,3-Triaminopropylphosphonates and 1,2-Diamino-3-Hydroxypropylphosphonates

Molecules, 2019
All possible isomers of 1,2,3-tri(N-tert-butoxycarbonylamino)propylphosphonate 6 were synthesized from the respective diethyl [N-(1-phenylethyl)]-1-benzylamino-2,3-epiiminopropylphosphonates 5 via opening the aziridine ring with trimethylsilyl azide ...
Aleksandra Trocha, Dorota G. Piotrowska, Iwona E. Głowacka   +2 more
doaj   +1 more source