Results 81 to 90 of about 1,369,818 (304)
The synthesis and ring-opening polymerisation of functionalised chiral O-carboxyanhydrides and cyclic carbonates [PDF]
This thesis presents the synthesis of two novel O-carboxyanhydrides derived from L-malic acid bearing 2,2,2-trichloroethyl- and 2-nitrobenzyl esters, followed by investigation of their ring-opening polymerisation to furnish chiral, functionalised poly ...
Bennison, Michael J.
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Photoinduced Ring Opening Copolymerization of Perfluoropolyalkylethers [PDF]
, 2018 Perfluoropolyalkylethers (PFPAEs), based on structural units such as –(CF2O)–, –(CF2CF2O)–, –(CF2CF2CF2O)– and –(CF(CF3)CF2O)–, represent a special class of fluoropolymers with remarkable properties (low glass transition temperature, high chemical and ...
Alessandra Vitale +7 more
core
Ring-Opening Hydroarylation of Monosubstituted Cyclopropanes Enabled by Hexafluoroisopropanol
, 2018 Ring-opening hydroarylation of cyclopropanes is typically limited to substrates bearing a donor-acceptor motif. Here, the transformation is achieved for monosubstituted cyclopropanes by using catalytic Brønsted acid in hexafluoroisopropanol (HFIP ...
Christopher Rowley +11 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Two-step ATP-driven opening of cohesin head
Scientific Reports, 2017 The cohesin ring is a protein complex composed of four core subunits: Smc1A, Smc3, Rad21 and Stag1/2. It is involved in chromosome segregation, DNA repair, chromatin organization and transcription regulation.
Íñigo Marcos-Alcalde +10 more
doaj +1 more source
, 2016 The palladium insertion polymerization catalysts (bipy)Pd(CH3)L+OTf- have been found to mediate a second class of polymerization reaction: the ring-opening polymerization of heterocycles.
Bruce A. Arndtsen (1310721) +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Free radical ring-opening polymerization [PDF]
Die Makromolekulare Chemie, 1985 Although unstrained five- or six-membered carbocyclic systems undergo free radical ring-closing polymerization, the introduction of an oxygen into the ring will promote free radical ring-opening polymerization, since the resulting carbon–oxygen double bond is approximately 50 kcal more stable than a carbon-carbon double bond.
openaire +1 more source