Results 131 to 140 of about 53,318 (258)

Prevalence of Subclinical Internal Jugular Vein Thrombosis After Microvascular Head and Neck Reconstruction

Microsurgery, Volume 46, Issue 1, January 2026.
ABSTRACT Background The risk of internal jugular vein thrombosis is a concern when using the internal jugular vein as a recipient vein in microvascular head and neck reconstruction. This study aimed to investigate the incidence of internal jugular vein thrombosis within 2 weeks of microvascular head and neck reconstruction using computed tomographic ...
Daichi Kurita, Shimpei Miyamoto, Yuki Saito, Kenya Kobayashi, Kou Fujisawa, Mutsumi Okazaki   +5 more
wiley   +1 more source

Assessing the link between rivaroxaban concentration and the onset of renal impairment in elderly patients: A retrospective observational study

Asian Journal of Medical Sciences
Background: Rivaroxaban is a widely used anticoagulant, but its impact on renal function, particularly at varying plasma concentrations, remains a critical area of investigation.
Motakatla Usha Rani , Chitra Karuppiah , Penupothu Sree Nagamani   +2 more
doaj   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

Efficacy and safety of rivaroxaban compared with warfarin in patients with peripheral artery disease and non-valvular atrial fibrillation: insights from ROCKET AF [PDF]

, 2013
W Schuyler Jones, Anne S. Hellkamp, J. Halperin, Jonathan P. Piccini, G Breithardt, Daniel E. Singer, Keith A.A. Fox, Kenneth W. Mahaffey, Robert M. Califf, M R Patel, ROCKET AF   +10 more
openalex   +1 more source

Characterizing Apixaban Pharmacokinetics Through Physiologically‐Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Apixaban, a factor Xa inhibitor, is a direct oral anticoagulant with a well‐balanced elimination; it is eliminated evenly via feces, urine (with no active secretion), and as metabolites after oral administration. The common understanding is that biliary secretion and enterohepatic circulation (EHC) of apixaban are limited in humans, and that ...
Toshiaki Tsuchitani, Wen Kou, Masatoshi Tomi, Yuichi Sugiyama   +3 more
wiley   +1 more source

Hampton's Hump as a Radiologic Clue to Pulmonary Embolism in a Young Patient

Respirology Case Reports, Volume 14, Issue 1, January 2026.
Pulmonary embolism may occur even in young adults with subtle risk factors such as prolonged immobility from mobile gaming. Despite the lungs' dual blood supply, pulmonary infarction can occur and is classically indicated by Hampton's hump, as seen on CT in this case.
Guo Li, Ming‐yan Jing, Min Pang
wiley   +1 more source

Evaluation of Two High‐Power Ablation Approaches in the Management of Typical Atrial Flutter: A Retrospective Study

Annals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
To compare the acute and long‐term outcomes of high‐power ablation for typical atrial flutter using a 4‐mm irrigated catheter (4‐IC) versus an 8‐mm non‐irrigated catheter (8‐NIC). We conducted a retrospective cohort study of 215 patients who underwent cavotricuspid isthmus (CTI) ablation between January 2019 and December 2024.
Hina Pervaiz, Farooq Hyder, Aimen Binte Moazzam, Fnu Abdullah, Abida Perveen, Jahanzeb Malik   +5 more
wiley   +1 more source

Bleeding Events Associated with Rivaroxaban Therapy in Naive Patients with Nonvalvular Atrial Fibrillation: A Longitudinal Study from a Genetic Perspective with INR Follow-Up

Medicina
Background and Objectives: Rivaroxaban is a direct-acting anticoagulant used to prevent stroke in patients with atrial fibrillation. Rivaroxaban is a substrate for P-glycoprotein, which is encoded by the ABCB1 gene. Rivaroxaban is also metabolized by the
Nur Ul Ain, Niaz Ali, Abid Ullah, Shakir Ullah, Shujaat Ahmad   +4 more
doaj   +1 more source

Bleeding Complication in a Patient with Concomitant Use of Rivaroxaban and Saffron Supplement: A Case Report [PDF]

, 2021
Maryam Daei, Hossein Khalili, Zinat Heidari   +2 more
openalex   +1 more source

Stability of Medications Administered via Enteral Feeding Tubes: A Systematic Review

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
The graphical abstract for the stability of medicatioins administred via enteral feeding tube: A systematic review ((PROSPERO, registration number: CRD42024580820)). ABSTRACT Feeding tubes are essential for patients unable to maintain adequate oral intake, serving multiple purposes including nutrition delivery and medication administration.
Lena Alodat, Wejdan Shahin, Lina Breik, Ayman Allahham   +3 more
wiley   +1 more source