Results 1 to 10 of about 18,957 (200)
Celecoxib effect on rivastigmine anti-Alzheimer activity against aluminum chloride-induced neurobehavioral deficits as a rat model of Alzheimer's disease; novel perspectives for an old drug [PDF]
Journal of Medical and Life Science, 2021 Neuroinflammation plays a crucial role in Alzheimer's disease (AD) pathogenesis. Apoptosis, along with impaired neurogenesis, has been linked to AD neurodegenerative cell death, likely due to overexpression of cyclooxygenase-2 (COX-2).
Raafat Abdel-Aal +3 more
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Rivastigmine lowers Aβ and increases sAPPα levels, which parallel elevated synaptic markers and metabolic activity in degenerating primary rat neurons. [PDF]
PLoS ONE, 2011 Overproduction of amyloid-β (Aβ) protein in the brain has been hypothesized as the primary toxic insult that, via numerous mechanisms, produces cognitive deficits in Alzheimer's disease (AD).
Jason A Bailey +3 more
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Use of a rivastigmine transdermic patch in Alzheimer's disease and Parkinson's disease dementia [PDF]
Romanian Journal of Neurology, 2009 Alzheimer’s disease and Parkinson’s disease dementia are becoming a public health issue. Given the therapeutic pitfalls in the elderly, there is a need of effective therapies. Rivastigmine, a cholinesterase inhibitor, emerges as an important agent in the
Lacramioara Perju Dumbrava +2 more
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Electrocardiographic Effects of Cholinesterase Inhibitors in Patients with Alzheimer’s Disease
Namık Kemal Tıp Dergisi, 2022 Aim:Cholinesterase inhibitors (ChEIs), such as donepezil and rivastigmine, are used safely in the treatment of Alzheimer’s disease (AD). However, the effects of these drugs on the cardiac conduction system are not clear.
Ayşe ÇOLAK, Didem ÖZ
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Rivastigmine alleviates experimentally induced colitis in mice and rats by acting at central and peripheral sites to modulate immune responses. [PDF]
PLoS ONE, 2013 The cholinergic anti-inflammatory system and α7 nicotinic receptors in macrophages have been proposed to play a role in neuroimmunomodulation and in the etiology of ulcerative colitis.
Helena Shifrin +3 more
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Frontiers in Pharmacology, 2022 Random skin flaps are frequently used to repair skin damage. However, the ischemic and hypoxic necrosis limits their wider application. Rivastigmine, a carbamate cholinesterase inhibitor (ChEI), has also been shown to reduce ischemia–reperfusion injury ...
Yingying Liu +6 more
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Indian Journal of Psychiatry, 2017 Objective: An important challenge in schizophrenia therapeutics is to develop an efficacious treatment for cognitive impairment. Acetylcholinesterase inhibitors, such as rivastigmine, have been studied for improving cognitive performance in these ...
Pattath Narayanan Suresh Kumar +3 more
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Alzheimer’s & Dementia: Translational Research & Clinical Interventions, 2019 Introduction The objective of the study was to assess adherence and persistence of patients treated with rivastigmine versus donepezil. Methods Persistence was calculated as the time from the first prescription date of rivastigmine/donepezil until ...
Chee‐Jen Chang +9 more
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Brain and Behavior, 2021 Background Visual hallucinations are common in patients with Parkinson's disease and represent probably the major independent predictor for cognitive deterioration and nursing home placement.
Tom J. M. vanMierlo +10 more
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International Journal of Gerontology, 2016 Rivastigmine is a well-known dual acting acetylcholinesterase and butyrylcholinesterase inhibitor, which is effective on behavioral and psychiatric symptoms including hallucinations, as well as cognitive symptoms of dementia.
Yıldız Değirmenci, Hulusi Keçeci
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