Results 61 to 70 of about 3,611 (194)

Absence of RKIP expression is an independent prognostic biomarker for gastric cancer patients [PDF]

, 2013
Gastric cancer is a leading cause of cancer-related mortality, and the presence of lymph node metastasis an important prognostic factor. Downregulation of RKIP has been associated with tumor progression and metastasis in several types of neoplasms, being
ADHEMAR LONGATTO-FILHO, Akaishi, Al-Mulla, Al-Mulla, Baritaki, Baritaki, Bernier, Bonavida, BRUNO ZILBERSTEIN, CARLOS EDUARDO JACOB, Chatterjee, Chatterjee, Chen, CLÁUDIO BRESCIANI, Crew, Desai, Dicken, Fenoglio-Preiser, Fu, Fu, Gabbert, Granovsky, Greene, Hagan, Hori, Houben, IVAN CECCONELLO, Jazirehi, Jia, JOAQUIM GAMA-RODRIGUES, KLEBER SIMÕES, Klysik, Lauren, Lee, Li, Lorenz, Martinho, Martinho, Martinho, Milne, Ming, Minoo, Minoo, OLGA MARTINHO, Pinheiro, RUI MANUEL REIS, Schuierer, Schuierer, Seddiqi, Utsunomiya, Vauhkonen, VENÂNCIO ALVES, Wang, Washington, Yeung, Yeung, Yeung, Yonemura, Zaravinos, Zhang, Zlobec   +60 more
core   +1 more source

RKIP downregulates B-Raf kinase activity in melanoma cancer cells [PDF]

Oncogene, 2005
The Raf-MEK-ERK protein kinase cascade is a highly conserved signaling pathway that is pivotal in relaying environmental cues from the cell surface to the nucleus. Three Raf isoforms, which share great sequence and structure similarities, have been identified in mammalian cells.
Sungdae, Park, Miranda L, Yeung, Sandy, Beach, Janiel M, Shields, Kam C, Yeung   +4 more
openaire   +2 more sources

The RhoA dependent anti-metastatic function of RKIP in breast cancer

Scientific Reports, 2021
Raf-1 kinase inhibitor protein was initially discovered as a physiological kinase inhibitor of the MAPK signaling pathway and was later shown to suppress cancer cell invasion and metastasis.
Gardiyawasam Kalpana, Christopher Figy, Jingwei Feng, Claire Tipton, Julius N. De Castro, Vu N. Bach, Clariza Borile, Alexandria LaSalla, Hussain N. Odeh, Miranda Yeung, Rafael Garcia-Mata, Kam C. Yeung   +11 more
doaj   +1 more source

An introduction to Biomodel engineering, illustrated for signal transduction pathways [PDF]

, 2009
BioModel Engineering is the science of designing, constructing and analyzing computational models of biological systems. It is inspired by concepts from software engineering and computing science.
Breitling, R, Donaldson, R, Gilbert, D, Heiner, M   +3 more
core   +1 more source

Solar Cell Light Trapping beyond the Ray Optic Limit [PDF]

, 2012
In 1982, Yablonovitch proposed a thermodynamic limit on light trapping within homogeneous semiconductor slabs, which implied a minimum thickness needed to fully absorb the solar spectrum.
Atwater, Harry A., Callahan, Dennis M., Munday, Jeremy N.   +2 more
core   +2 more sources

Bmi-1-induced miR-27a and miR-155 promote tumor metastasis and chemoresistance by targeting RKIP in gastric cancer

Molecular Cancer, 2020
Background We previously reported an inverse relationship between B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) and Raf kinase inhibitory protein (RKIP), which is associated with the prognosis of gastric cancer (GC).
Yaqing Li, Zhenfeng Tian, Ying Tan, Guoda Lian, Shangxiang Chen, Shaojie Chen, Jiajia Li, Xuanna Li, Kaihong Huang, Yinting Chen   +9 more
doaj   +1 more source

Urinary RKIP/p-RKIP is a potential diagnostic and prognostic marker of clear cell renal cell carcinoma

Oncotarget, 2017
Clear cell Renal Cell Carcinoma (ccRCC) causes over 13,000 deaths each year, and about 20,000 new cases/year in Europe. In most cases, the causes are unknown and, most importantly, there are no reliable biomarkers for the diagnosis and prognosis of this disease.
Papale M., Vocino G., Lucarelli G., Rutigliano M., Gigante M., Rocchetti M. T., Pesce F., Sanguedolce F., Bufo P., Battaglia M., Stallone G., Grandaliano G., Carrieri G., Gesualdo L., Ranieri E.   +14 more
openaire   +5 more sources

The Multifaceted Roles of BACH1 in Disease: Implications for Biological Functions and Therapeutic Applications

Advanced Science, Volume 12, Issue 10, March 13, 2025.
BACH1, a basic leucine zipper protein ubiquitously expressed in mammalian tissues, plays a critical role in the regulation of oxidative stress, cell cycle progression, heme homeostasis, and immune responses. It is implicated in cardiovascular diseases, cancer progression, neurodegenerative disorders, and many other diseases.
Xiangxiang Wei, Yunquan He, Yueyang Yu, Sichong Tang, Ruiwen Liu, Jieyu Guo, Qingjun Jiang, Xiuling Zhi, Xinhong Wang, Dan Meng   +9 more
wiley   +1 more source

Abstracts

, 2023
Molecular Oncology, Volume 17, Issue S1, Page 1-597, June 2023.
wiley   +1 more source

Expression and Significance of Raf Kinase Inhibitory Protein 
in Lung Cancer

Chinese Journal of Lung Cancer, 2012
Background and objective Raf kinase inhibitory protein (RKIP) belongs to the phosphatidylethanolamine binding protein family. RKIP is an endogenous inhibitor of the ERK/MAPK, NF-κΒ, and G protein-coupled receptor signaling pathways.
Dayun YANG, Zhan QI
doaj   +1 more source