Results 71 to 80 of about 1,582 (158)
The molecular biology of NF2/Merlin on tumorigenesis and development
The FASEB Journal, Volume 38, Issue 13, 15 July 2024.Depiction of NF2/Merlin domain structure, organization, and function. Merlin consists of the N‐terminal FERM domain (blue), comprising three subdomains (A, B, and C), a central helical domain (purple), and a C‐terminal domain (CTD, gray). NF2 mutations based on location and their clinical manifestations are shown below the exon scheme indicated by a ...
Rexhina Vlashi +5 more
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CNS Neuroscience &Therapeutics, Volume 30, Issue 7, July 2024.Blood–brain barrier disruption and immune system infiltration after intracerebral hemorrhage. Abstract Aims Intracerebral hemorrhage (ICH) is a condition that arises due to the rupture of cerebral blood vessels, leading to the flow of blood into the brain tissue.
Peijun Jia +16 more
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Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma
Journal of Experimental & Clinical Cancer Research, 2017 Multiple myeloma (MM) is a clonal plasma-cell neoplastic disorder arising from an indolent premalignant disease known as monoclonal gammopathy of undetermined significance (MGUS).
Anna Shvartsur +3 more
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Cyclin‐dependent kinase 5 (CDK5) inhibitors in Parkinson disease
Journal of Cellular and Molecular Medicine, Volume 28, Issue 11, June 2024.Abstract Cyclin‐dependent kinase 5 (Cdk5) is a protein expressed in postmitotic neurons in the central nervous system (CNS). Cdk5 is activated by p35 and p39 which are neuron regulatory subunits. Cdk5/p35 complex is activated by calpain protease to form Cdk5/p35 which has a neuroprotective effect by regulating the synaptic plasticity and memory ...
Mohammed Alrouji +7 more
wiley +1 more source
Influence of RKIP Protein Complexes Concentrations on the Quasi-Stationary Behaviour of the MEK/ERK Signal Transduction Pathway [PDF]
Bioautomation, 2007 It is considered the quasi-stationary approximation of a dynamic model, representing a positive feedback mechanism in the MEK/ERK signaling pathway mediated by RKIP.
Petrov V., Nikolova E.
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Microgravity effect on expressionofRaf kinase inhibitor protein on MCF-7 breast cancer cell line [PDF]
مجله علمی دانشگاه علوم پزشکی کردستان, 2019 Background and Aim: The living organisms on the earth are under the influence of natural gravity force and if this gravitational force changes, they will be affected by a unique shock.
Maryam Salavatifar, Zahra Hajebrahimi
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Journal of Lipid Research, 2013 Chronic exposure of skeletal muscle to saturated fatty acids, such as palmitate (C16:0), enhances proinflammatory IKK-NFκB signaling by a mechanism involving the MAP kinase (Raf-MEK-ERK) pathway. Raf activation can be induced by its dissociation from the
Katherine Macrae +7 more
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Cancer Management and Research, 2021 Gong Z, Chen X, Zhang Y, et al. Cancer Manag Res. 2020;12:9327–9338. The Editor and Publisher of Cancer Management and Research wish to publish an Expression of Concern for the published article.
Gong Z +7 more
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Role of microRNAs in the regulation of RKIP and signaling pathways in cancer
Biochimica et Biophysica Acta (BBA) - Reviews on CancerRaf kinase inhibitor protein (RKIP), also known as Phosphatidyl Ethanolamine Binding Protein (PEBP1), is a pivotal modulator of multiple intracellular signaling cascades involved in tumorigenesis, progression, metastasis, and cancer therapy resistance.
Spoto, Graziana +2 more
openaire +2 more sources
Cancer Management and Research, 2020 Zixuan Gong,1,* Xiaoyu Chen,2,* YueChao Zhang,3,* Cheng Liu,4 Zhibing Wang,5 Xiaoyan Xu,6 Jun Zhu,7 Tongqing Xue4 1Department of Urology, Jiangsu Provincial People’s Hospital, Nanjing, Jiangsu Province, 211166, People’s Republic of China ...
Gong Z +7 more
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