Results 31 to 40 of about 150,391 (120)

Preventive Gastroprotective Effect of a Functional Food Based on Quinoa (Chenopodium quinoa Willd.) and Quercetin in a Murine Model of Ibuprofen-Induced Gastric Damage

Antioxidants
Nonsteroidal anti-inflammatory drug-based therapies are the cause of 20–30% cases of gastric lesions in chronic users worldwide. Co-medication with omeprazole (OMP) is the most commonly used option to prevent these lesions, although this carries risks of
Maribel Valenzuela-González, José Luis Cárdenas-López, Armando Burgos-Hernández, Norma Julieta Salazar-López, Manuel Viuda-Martos, Mónica A. Villegas-Ochoa, Gustavo Martínez-Coronilla, J. Abraham Domínguez-Avila, Shela Gorinstein, Gustavo A. González-Aguilar, Rosario Maribel Robles-Sánchez   +10 more
doaj   +1 more source

Antioxidant and Anti-Inflammatory Effects of Crude Gastrodia elata Polysaccharides in UVB-Induced Acute Skin Damage

Antioxidants
Ultraviolet B (UVB) irradiation drives skin photodamage, prompting exploration of natural therapeutics. This study investigated the reparative effects and mechanisms of crude Gastrodia elata polysaccharides (GP) on UVB-induced acute skin damage.
Jiajia Liu, Xiaoqi Yang, Xing Huang, Yuan Luo, Qilin Zhang, Feng Wang, Yicen Lin, Lianbing Lin   +7 more
doaj   +1 more source

Exploring the biological basis for the identification of different syndromes in ischemic heart failure based on joint multi-omics analysis

Frontiers in Pharmacology
BackgroundIHF is a major chronic disease that seriously threatens human health. Qi deficiency and blood stasis syndrome (QDBS), Yang deficiency with blood stasis syndrome (YDBS) and Yang deficiency and blood stasis with fluid retention syndrome (YDBSFR ...
Yilin Zhang, Yilin Zhang, Jingjing Wei, Lijie Qiao, Rui Yu, Hongjie Ren, Anshe Zhao, Yang Sun, Aolong Wang, Aolong Wang, Bin Li, Xinlu Wang, Mingjun Zhu   +12 more
doaj   +1 more source

Nano-Amounts of Glucagon Premixed With Fast-Acting Insulin Lispro: Effect on Insulin Absorption in Pigs

Current Therapeutic Research
Background: Glucagon leads to substantial but short-lived subcutaneous vasodilation. Using micro-amounts of glucagon at the insulin injection site increases insulin absorption.
Ilze Dirnena-Fusini, PhD, Misbah Riaz, MSc, Sverre Christian Christiansen, MD, PhD, Sven Magnus Carlsen, MD, PhD   +3 more
doaj   +1 more source

Exosomal non-coding RNAs: gatekeepers of inflammation in autoimmune disease

Journal of Inflammation
Autoimmune diseases (AIDs) are marked by systemic inflammation and immune dysregulation, yet current therapies often fail to target their underlying causes.
Mohamed J. Saadh, Omer Qutaiba B. Allela, Ali Fawzi Al-Hussainy, Lalji Baldaniya, M. M. Rekha, Deepak Nathiya, Parjinder Kaur, Zafar Aminov, Hayder Naji Sameer, Huda Ghassan Hameed, Zainab H. Athab, Mohaned Adil   +11 more
doaj   +1 more source

The antipsychotics functional index (AFI) in schizophrenia

Frontiers in Pharmacology
Schizophrenia can lead to significant and long-lasting deficits in patient functionality. The present study proposes a theoretical index that predicts the ability of an antipsychotic to improve the functionality of patients with schizophrenia.
Gabriel-Cristian Marinescu, Petru Iulian Ifteni, Andreea Teodorescu, Radu Georgescu   +3 more
doaj   +1 more source

Pharmacological targeting of ferroptosis in hypoxia-induced pulmonary edema: therapeutic potential of ginsenoside Rg3 through activation of the PI3K/AKT pathway

Frontiers in Pharmacology
BackgroundHigh-altitude pulmonary edema (HAPE), a severe manifestation of hypoxia-induced pulmonary hypertension, continues to present a major health concern in high-altitude environments due to the absence of efficient preventive measures.
Yacong He, Yilang Wang, Huxinyue Duan, Demei Huang, Nan Jia, Zherui Shen, Zhenxing Wang, Mingjie Wang, Tianzhu Zhao   +8 more
doaj   +1 more source

Therapeutic effects and mechanism analysis of Paeonia lactiflora extract (PLE) in menopausal rats with hot flashes

Frontiers in Pharmacology
Ethnopharmacological relevanceMenopausal syndrome (MPS) is a symptom of physical and psychosomatic abnormalities that women may face around the time of menopause. Hot flashes are the main symptom. Paeonia lactiflora extract (PLE) is the active ingredient
Weilin Cui, Tingting Song, Dongmei Gao, Xiaoyu Wang, Ya Sun, Liyu Fu, Yichao Han, Jieqiong Wang   +7 more
doaj   +1 more source

Cannabidiol reduces synaptic strength and neuronal firing in layer V pyramidal neurons of the human cortex with drug-resistant epilepsy

Frontiers in Pharmacology
The use of cannabidiol (CBD) as an alternative pharmacological approach for the symptomatic management of epilepsy has gained attention due to its potential efficacy, particularly in drug-resistant cases of epilepsy.
Vladimir A. Martinez-Rojas, Luis A. Márquez, Christopher Martinez-Aguirre, Isabel Sollozo-Dupont, Félix Iván López Preza, Monserrat Fuentes Mejía, Mario Alonso, Luisa Rocha, Emilio J. Galván, Emilio J. Galván   +9 more
doaj   +1 more source

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, 1982
Journal of Analytical Methods in Chemistry, Volume 4, Issue 4, Page 197-210, 1982.
wiley   +1 more source