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Mechanisms of catalytic RNA molecules

Biochemical Society Transactions, 2021
Ribozymes are folded catalytic RNA molecules that perform important biological functions. Since the discovery of the first RNA with catalytic activity in 1982, a large number of ribozymes have been reported. While most catalytic RNA molecules act alone, some RNA-based catalysts, such as RNase P, the ribosome, and the spliceosome, need protein ...
Dulce Alonso, Alfonso Mondragón
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The catalytic diversity of RNAs

Nature Reviews Molecular Cell Biology, 2005
The natural RNA enzymes catalyse phosphate-group transfer and peptide-bond formation. Initially, metal ions were proposed to supply the chemical versatility that nucleotides lack. In the ensuing decades, structural and mechanistic studies have substantially altered this initial viewpoint.
Martha J, Fedor, James R, Williamson
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