Results 21 to 30 of about 298,718 (298)

CIRCexplorer3: A CLEAR Pipeline for Direct Comparison of Circular and Linear RNA Expression

Genomics, Proteomics & Bioinformatics, 2019
Sequences of circular RNAs (circRNAs) produced from back-splicing of exon(s) completely overlap with those from cognate linear RNAs transcribed from the same gene loci with the exception of their back-splicing junction (BSJ) sites. Therefore, examination
Xu-Kai Ma, Meng-Ran Wang, Chu-Xiao Liu, Rui Dong, Gordon G. Carmichael, Ling-Ling Chen, Li Yang   +6 more
doaj   +1 more source

Mechanisms of circular RNA degradation

Communications Biology, 2022
In this Perspective, Longxin Ren and co-authors summarise the role of circular RNAs in disease and discuss recent insights into how circular RNAs are metabolised in the cell.
Longxin Ren, Qingshan Jiang, Liyi Mo, Lijie Tan, Qifei Dong, Lijuan Meng, Nanyang Yang, Guoqing Li   +7 more
doaj   +1 more source

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons [PDF]

, 2017
The RNA-binding protein FUS participates in several RNA biosynthetic processes and has been linked to the pathogenesis of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.
Bozzoni, Irene, Caffarelli, Elisa, Capauto, Davide, Colantoni, Alessio, DE SANTIS, Riccardo, DINI MODIGLIANI, Stefano, Errichelli, Lorenzo, Laneve, Pietro, Legnini, Ivano, Lu, Lei, Morlando, Mariangela, Peruzzi, Giovanna, Rosa, Alessandro, Scarfò, Rebecca, Shneider, Neil A.   +14 more
core   +1 more source

Expression profile of circular RNA and construction of circular RNA-Micro RNA network in salivary adenoid cystic carcinoma

Cancer Cell International, 2021
Background Circular RNAs (circRNAs) is a newly discovered type of non-coding RNA, the abnormal expression of which has been demonstrated in many types of human tumors.
Jing Han, Nannan Han, Zhimin Xu, Chunye Zhang, Jiannan Liu, Min Ruan   +5 more
doaj   +1 more source

Circular RNA in Diseased Heart

Cells, 2020
Heart disease remains the leading cause of death globally and leads to tremendous socio-economic burden. Despite advances in the field of cardiovascular research, novel theranostics are still in urgent need.
Ying Wang, Bin Liu
doaj   +1 more source

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W., Davidson, Norman, Mullins, James I., Nicolson, Margery O.   +3 more
core   +1 more source

Circular RNA: A Potential Biomarker for Lung Cancer

Zhongliu Fangzhi Yanjiu, 2019
Circular RNA is a non-coding RNA that acts as a sponge for RNA, regulates cleavage and transcription, translates proteins and interacts with RNA-binding proteins.
XIAO Zhihao, XIAO Yao, LU Xiaodan, LI Wendan   +3 more
doaj   +1 more source

Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance

Technology in Cancer Research & Treatment, 2021
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM, Bing Liu MD, Shaolei Li PhD, Yang Hong PhD, Jiahui Si PhD, Ying Xiong MSc, Nan Wu MD, Yuanyuan Ma PhD   +7 more
doaj   +1 more source

Circular RNA and tumor microenvironment

Cancer Cell International, 2020
Circular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological processes.
Huixin Song, Qiaofei Liu, Quan Liao
doaj   +1 more source

Circular RNA identified from Peg3 and Igf2r. [PDF]

PLoS ONE, 2018
Circular RNA is a newly discovered class of non-coding RNA generated through the back-splicing of linear pre-mRNA. In the current study, we characterized two circular RNAs that had been identified through NGS-based 5'RACE experiments.
Bambarendage P U Perera, Subash Ghimire, Joomyeong Kim   +2 more
doaj   +1 more source