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What goes around comes around: Artificial circular RNAs bypass cellular antiviral responses
Molecular Therapy: Nucleic Acids, 2022 Natural circular RNAs have been found to sequester microRNAs and suppress their function. We have used this principle as a molecular tool and produced artificial circular RNA sponges in a cell-free system by in vitro transcription and ligation. Formerly,
Janina Breuer +6 more
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Sequence organization of feline leukemis virus DNA in infected cells [PDF]
, 1980 A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W. +3 more
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CIRCexplorer3: A CLEAR Pipeline for Direct Comparison of Circular and Linear RNA Expression
Genomics, Proteomics & Bioinformatics, 2019 Sequences of circular RNAs (circRNAs) produced from back-splicing of exon(s) completely overlap with those from cognate linear RNAs transcribed from the same gene loci with the exception of their back-splicing junction (BSJ) sites. Therefore, examination
Xu-Kai Ma +6 more
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Cancer Cell International, 2021 Background Circular RNAs (circRNAs) is a newly discovered type of non-coding RNA, the abnormal expression of which has been demonstrated in many types of human tumors.
Jing Han +5 more
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Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis [PDF]
, 2017 Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is fairly well characterized, whereas their role in the modulation of ...
Andronache, Adrian +12 more
core +3 more sources
Circular RNA in Diseased Heart
Cells, 2020 Heart disease remains the leading cause of death globally and leads to tremendous socio-economic burden. Despite advances in the field of cardiovascular research, novel theranostics are still in urgent need.
Ying Wang, Bin Liu
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Technology in Cancer Research & Treatment, 2021 Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM +7 more
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The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]
, 2018 The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni +3 more
core +1 more source
Circular RNA: A Potential Biomarker for Lung Cancer
Zhongliu Fangzhi Yanjiu, 2019 Circular RNA is a non-coding RNA that acts as a sponge for RNA, regulates cleavage and transcription, translates proteins and interacts with RNA-binding proteins.
XIAO Zhihao +3 more
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Circular RNA and tumor microenvironment
Cancer Cell International, 2020 Circular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological processes.
Huixin Song, Qiaofei Liu, Quan Liao
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