Results 21 to 30 of about 163,376 (265)

CIRCexplorer3: A CLEAR Pipeline for Direct Comparison of Circular and Linear RNA Expression

Genomics, Proteomics & Bioinformatics, 2019
Sequences of circular RNAs (circRNAs) produced from back-splicing of exon(s) completely overlap with those from cognate linear RNAs transcribed from the same gene loci with the exception of their back-splicing junction (BSJ) sites. Therefore, examination
Xu-Kai Ma, Meng-Ran Wang, Chu-Xiao Liu, Rui Dong, Gordon G. Carmichael, Ling-Ling Chen, Li Yang   +6 more
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Circular RNA in Diseased Heart

Cells, 2020
Heart disease remains the leading cause of death globally and leads to tremendous socio-economic burden. Despite advances in the field of cardiovascular research, novel theranostics are still in urgent need.
Ying Wang, Bin Liu
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Mechanisms of circular RNA degradation

Communications Biology, 2022
In this Perspective, Longxin Ren and co-authors summarise the role of circular RNAs in disease and discuss recent insights into how circular RNAs are metabolised in the cell.
Longxin Ren, Qingshan Jiang, Liyi Mo, Lijie Tan, Qifei Dong, Lijuan Meng, Nanyang Yang, Guoqing Li   +7 more
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Circular RNA in gastric cancer

Chinese Medical Journal, 2020
. Gastric cancer (GC) is a common malignancy and is the third leading cause of cancer-related death. At present, there is no simple and effective screening method for early-stage GC, and the treatment results and prognosis are poor.
Xue-Wei Li, Wen-Hui Yang, Jun Xu, Qiang Shi   +3 more
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Expression profile of circular RNA and construction of circular RNA-Micro RNA network in salivary adenoid cystic carcinoma

Cancer Cell International, 2021
Background Circular RNAs (circRNAs) is a newly discovered type of non-coding RNA, the abnormal expression of which has been demonstrated in many types of human tumors.
Jing Han, Nannan Han, Zhimin Xu, Chunye Zhang, Jiannan Liu, Min Ruan   +5 more
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Circular RNA: A Potential Biomarker for Lung Cancer

Zhongliu Fangzhi Yanjiu, 2019
Circular RNA is a non-coding RNA that acts as a sponge for RNA, regulates cleavage and transcription, translates proteins and interacts with RNA-binding proteins.
XIAO Zhihao, XIAO Yao, LU Xiaodan, LI Wendan   +3 more
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Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance

Technology in Cancer Research & Treatment, 2021
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM, Bing Liu MD, Shaolei Li PhD, Yang Hong PhD, Jiahui Si PhD, Ying Xiong MSc, Nan Wu MD, Yuanyuan Ma PhD   +7 more
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Circular RNA and tumor microenvironment

Cancer Cell International, 2020
Circular RNAs (circRNAs) are small non-coding RNAs with a unique ring structure and play important roles as gene regulators. Disturbed expressions of circRNAs is closely related to varieties of pathological processes.
Huixin Song, Qiaofei Liu, Quan Liao
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Interior circular RNA [PDF]

RNA Biology, 2019
Formed by back splicing or back fusion of linear RNAs, circular RNAs (circRNAs) constitute a new class of non-coding RNAs of eukaryotes. Recent studies reveal a spliceosome-dependent biogenesis of circRNAs where circRNAs arise at the intron-exon junctions of mRNAs.
Xiaoxin Liu, Zhangfeng Hu, Junfei Zhou, Cheng Tian, Guangmei Tian, Miao He, Lifen Gao, Lihong Chen, Tiantian Li, Hai Peng, Weixiong Zhang   +10 more
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Circular RNA identified from Peg3 and Igf2r. [PDF]

PLoS ONE, 2018
Circular RNA is a newly discovered class of non-coding RNA generated through the back-splicing of linear pre-mRNA. In the current study, we characterized two circular RNAs that had been identified through NGS-based 5'RACE experiments.
Bambarendage P U Perera, Subash Ghimire, Joomyeong Kim   +2 more
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