Results 251 to 260 of about 132,574 (309)

Small Nuclear RNA U2 Is Base-Paired to Heterogeneous Nuclear RNA

Science, 1982
Eukaryotic cells contain a set of low molecular weight nuclear RNA's. One of the more abundant of these is termed U2 RNA. The possibility that U2 RNA is hydrogen-bonded to complementary sequences in other nuclear RNA's was investigated. Cultured human (HeLa) cells were treated with a psoralen derivative that cross-links RNA chains that are base-paired ...
J P, Calvet, L M, Meyer, T, Pederson
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Subnuclear particles containing a small nuclear RNA and heterogeneous nuclear RNA

Journal of Molecular Biology, 1981
Abstract Five of the stable low molecular weight RNA species in the HeLa cell nucleus have been localized in RNP complexes in the cell nucleus. The two abundant species C and D and the three minor species F, G′ and H are found in RNP particles following two different methods of preparation.
G, Zieve, S, Penman
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The status of small nuclear RNA in the ribonucleoprotein fibrils containing heterogeneous nuclear RNA

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1981
hnRNP are made of two classes of unit, monoparticles and heterogeneous complexes. The monoparticles are much more easily dissociated by salt than the heterogeneous complexes. We made use of this differential salt sensitivity to determine the localization of snRNA in hnRNP.
H, Gallinaro, M, Jacob
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A COMPARISON OF THE HETEROGENEOUS NUCLEAR RNA OF HELA CELLS IN DIFFERENT PERIODS OF THE CELL GROWTH CYCLE [PDF]

Journal of Cell Biology, 1970
HeLa cells synthesize heterogeneous nuclear RNA (HnRNA) in the G(1), S, and G(2) portions of the cell cycle. HnRNA prepared from these various periods was compared by RNA-DNA hybridization experiments.
Gerassimos N Pagoulatos, James E Darnell, Darnell James E   +2 more
exaly   +2 more sources

Processing of nuclear heterogeneous RNA: Recent developments

Life Sciences, 1977
Abstract The biogenesis of eucaryotic messenger ribonucleic acid (mRNA) has been under intense investigation in many laboratories over the past decade. A number of new experimental observations have contributed much to our understanding of the possible relationship between heterogeneous nuclear RNA (hnRNA) and cytoplasmic mRNA.
L, Chan, S E, Harris, J M, Rosen, A R, Means, B W, O'Malley   +4 more
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Stabilization of heterogeneous nuclear RNA by intercalating drugs

Biochemical and Biophysical Research Communications, 1973
The effect of the intercalating drugs proflavine, ethidium and daunomycin on the rate of degradation of 14C-labeled heterogeneous nuclear RNA (HnRNA) in KB cells was studied. All three drugs decreased the rate of degradation of 14C-HnRNA to acid soluble products.
J M, Brinker, H P, Madore, L J, Bello
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Heterogeneous Nuclear Ribonucleoproteins: Role in RNA Splicing

Science, 1986
Splicing in vitro of a messenger RNA (mRNA) precursor (pre-mRNA) is inhibited by a monoclonal antibody to the C proteins (anti-C) of the heterogeneous nuclear RNA (hnRNA)-ribonucleoprotein (hnRNP) particles. This antibody, 4F4, inhibits an early step of the reaction: cleavage at the 3′ end of the upstream exon and the formation of the ...
Y D, Choi, P J, Grabowski, P A, Sharp, G, Dreyfuss   +3 more
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The Poly(A) Sequences in Messenger RNA and Heterogeneous Nuclear RNA

1974
The poly(A) sequences covalently bound both to the heterogeneous RNA (HnRNA) of the nucleus and to the polysome-bound messenger RNA (mRNA) of many eukaryotes (1–3) have provided chemical evidence for the precursor- product relationship long predicted to link these two species of RNA.
H, Nakazato, M, Edmonds
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Structure of late adenovirus 2 heterogeneous nuclear RNA

Journal of Molecular Biology, 1979
Abstract Late adenovirus 2 messenger RNAs are processed from a single transcriptional unit some 20,000 nucleotides in length. All of these cytoplasmic RNAs have multiple leaders spliced to their 5′ termini; the most common form is a tripartite leader set.
S M, Berget, P A, Sharp
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Proteins Associated with Heterogeneous Nuclear RNA of Newt Oocytes

Nature New Biology, 1973
RAPIDLY labelled, high molecular weight RNA, with a DNA-like base composition, is synthesized on oocyte lampbrush chromosomes of the newt, Triturus cristatus carnifex1. This RNA resembles the heterogeneous nuclear RNA (HnRNA) found in other systems2 and when isolated is found to be associated with large amounts (>97%) of non-basic proteins in the form ...
J, Sommerville, R J, Hill
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