Results 91 to 100 of about 162,179 (208)

Genome-wide analysis of long noncoding RNA stability [PDF]

, 2012
Transcriptomic analyses have identified tens of thousands of intergenic, intronic, and cis-antisense long noncoding RNAs (lncRNAs) that are expressed from mammalian genomes.
Clark, Michael B., Dinger, Marcel E., Fortini, Ellen, Fox, Archa H., Inostroza-Ponta, Mario, Johnston, Rebecca L., Mattick, John S., Moscato, Pablo   +7 more
core   +1 more source

The lincRNA MIRAT binds to IQGAP1 and modulates the MAPK pathway in NRAS mutant melanoma. [PDF]

, 2018
Despite major advances in targeted melanoma therapies, drug resistance limits their efficacy. Long noncoding RNAs (lncRNAs) are transcriptome elements that do not encode proteins but are important regulatory molecules.
Burlingame, Alma, Daud, Adil, Dimon, Michelle, Esteve-Puig, Rosaura, Gajjala, Abhinay, Gho, Deborah, Ho, Wilson, Johnston, Katia, Lai, Kevin, Lin, Kevin, Moy, Adrian, Ortiz-Urda, Susana, Oses Prieto, Juan, Posch, Christian, Rappersberger, Klemens, Sanlorenzo, Martina, Vujic, Igor, Vujic, Marin, Zekhtser, Mitchell   +18 more
core   +1 more source

Force for ancient and recent life: viral and stem-loop RNA consortia promote life. [PDF]

, 2014
Lytic viruses were thought to kill the most numerous host (i.e., kill the winner). But persisting viruses/defectives can also protect against viruses, especially in a ubiquitous virosphere. In 1991, Yarmolinsky et al.
Villarreal, Luis P
core   +1 more source

Expression profiling of snoRNAs in normal hematopoiesis and AML [PDF]

, 2018
Key Points A subset of snoRNAs is expressed in a developmental- and lineage-specific manner during human hematopoiesis. Neither host gene expression nor alternative splicing accounted for the observed differential expression of snoRNAs in ...
Helton, Nichole, Ley, Timothy J., Link, Daniel C., Spencer, David H., Trissal, Maria, Warner, Wayne A., White, Brian S.   +6 more
core   +2 more sources

ZFAS1: a novel tumor-related long non-coding RNA

Cancer Cell International, 2018
Long non-coding RNAs (lncRNA) are classified as a kind of RNA, which are longer than 200 nucleotides in length and cannot be translated into proteins. Multiple studies have demonstrated that lncRNAs are involved in various cellular processes, including ...
Dan Dong, Zhongyi Mu, Chenghai Zhao, Mingli Sun   +3 more
doaj   +1 more source

The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development [PDF]

, 2016
Long noncoding RNA (lncRNA) may contribute to the initiation and progression of tumor. In this study, we first systematically compared lncRNA and mRNA expression between glioblastoma and paired normal brain tissues using microarray data.
Eischen, Christine M., Fan, Wenhong, Liu, Shuang, Mitra, Ramkrishna, Yin, Feng, Zhao, Ming-Ming, Zhao, Zhongming   +6 more
core   +2 more sources

Long Noncoding RNAs and Hepatocellular Carcinoma

Gastroenterology, 2015
openAccessArticle: False ; cover date: 2015-02-01 ; pii: S0016-5085(14)01536-4 ; Harvest Date: 2016-01-06 13:07:54 ; issueName: ; Page Range: 291-291 ; href scidir: http://www.sciencedirect.com/science/article/pii/S0016508514015364 ; pubType ...
James F., Collins, Collins, James F.
openaire   +3 more sources

The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43

, 2019
The cellular and the molecular mechanisms by which long noncoding RNAs (lncRNAs) may regulate presynaptic function and neuronal activity are largely unexplored.
Bansal, V., Bonn, S., Fornasiero, E., Fritsch, E., Gomes, L., Gärtner, A., Keihani, S., Klüver, V., Kügler, S., Mandad, S., Rahman, R., Rizzoli, S., Urlaub, H., Wren, J.   +13 more
core   +1 more source

The fate of Arabidopsis thaliana homeologous CNSs and their motifs in the Paleohexaploid Brassica rapa. [PDF]

, 2013
Following polyploidy, duplicate genes are often deleted, and if they are not, then duplicate regulatory regions are sometimes lost. By what mechanism is this loss and what is the chance that such a loss removes function?
Freeling, Michael, Pires, J, Subramaniam, Sabarinath, Wang, Xiaowu   +3 more
core   +2 more sources

Revealing potential long non-coding RNA biomarkers in lung adenocarcinoma using long non-coding RNA-mediated competitive endogenous RNA network

Brazilian Journal of Medical and Biological Research
In our study, we aimed to reveal potential long non-coding RNAs (lncRNA) biomarkers in lung adenocarcinoma (LAD) using lncRNA-mediated competing endogenous RNAs (ceRNAs) network (LMCN).
T-G. Zhu, X. Xiao, Q. Wei, M. Yue, L-X. Zhang   +4 more
doaj   +1 more source