Results 181 to 190 of about 111,170 (313)

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

Obstructive sleep apnea and major depressive disorder: Shared transcriptional signatures and candidate pathways identified via bioinformatics analysis

open access: yesSleep Research, EarlyView.
Abstract Background Obstructive sleep apnea (OSA) frequently co‐occurs with major depressive disorder (MDD). However, the underlying biological mechanisms remain unclear. This study aimed to identify OSA‐related transcriptional signatures associated with depressive status using integrated bioinformatics and machine learning.
Yun‐Shu Sun   +5 more
wiley   +1 more source

RNA‐DNA Fusomer Fibers With Customizable Physicochemical, Mechanical, and Biological Properties for Next‐Generation Therapeutics

open access: yesSmall, EarlyView.
ABSTRACT We introduce RNA‐DNA fusomers, a new class of chemically synthesized oligonucleotides that combine the versatile properties of RNA and DNA within a single sequence and self‐assemble into higher‐order functional structures via a simple one‐pot annealing reaction.
Yasmine Radwan   +21 more
wiley   +1 more source

Editorial: RNA-chromatin interactions: biology, mechanism, disease, and therapeutics—volume 2

open access: yesFrontiers in Genetics
Malik Bisserier   +3 more
doaj   +1 more source

Engineering Nanoscale Frontiers: Valve Metal Oxide Nanostructures From Fundamentals to Multifunctional Biomedical Applications

open access: yesThe Chemical Record, EarlyView.
Valve metal oxide nanostructures such as TiO2, Ta2O5, Nb2O5, ZrO2, and HfO2 are emerging as versatile biomedical platforms due to their tunable surface properties, exceptional stability, and inherent biocompatibility. This review highlights their synthesis, physicochemical properties, and biological interactions, addressing their roles in advanced ...
Nina Kummer   +11 more
wiley   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

open access: yesUroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Long Noncoding RNAs

open access: yesJournal of the American College of Cardiology, 2016
Boon, Reinier A.   +3 more
openaire   +1 more source

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