Results 201 to 210 of about 8,401,372 (300)

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

open access: yesThe FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon   +4 more
wiley   +1 more source

Corrigendum: Profiling the long noncoding RNA interaction network in the regulatory elements of target genes by chromatin in situ reverse transcription sequencing. [PDF]

open access: yesGenome Res
Zhang S   +27 more
europepmc   +1 more source

Epigenetic and Metabolic Changes That Drive Trained Immunity in Response to Microbes and Vaccines

open access: yesImmunology, EarlyView.
This graphical abstract illustrates how microbial products, vaccines and microbial metabolites activate pattern‐recognition receptor signalling, inducing metabolic rewiring and epigenetic remodelling. These changes establish long‐lasting trained immunity through the functional reprogramming of haematopoietic progenitors and innate immune cells, thereby
Desalegn Abebaw   +10 more
wiley   +1 more source

Isolation and Identification of Erysipelothrix sp. in Hybrid Grouper (Epinephelus fuscoguttatus × E. lanceolatus) in Taiwan

open access: yesJournal of Fish Diseases, EarlyView.
ABSTRACT In February 2025, a mortality event of unknown aetiology occurred at a hybrid grouper (Epinephelus fuscoguttatus × Epinephelus lanceolatus) aquaculture farm in southern Taiwan, with sporadic daily deaths persisting for a month. Four moribund groupers were collected over three sampling intervals for diagnostic investigation.
Shang‐Ting Wu   +2 more
wiley   +1 more source

Climate‐driven niche filtering limits post‐dispersal establishment and genomic introgression in a riverine shrub

open access: yesJournal of Integrative Plant Biology, EarlyView.
Integrated biogeographic analysis and macroecological insights reveal that habitat differences drive genetic differentiation Debregeasia orientalis C. J. Chen, a dominant riparian shrub distributed across multiple biodiversity hotspots, and different lineages vary greatly in adaptability to future climate.
Zeng‐Yuan Wu   +12 more
wiley   +1 more source

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