Results 221 to 230 of about 111,170 (313)

Sequential sequencing reveals the architecture and complexity of genomic variants in patients with Alport syndrome. [PDF]

Nat Commun
Di H, You Z, Wang L, Sun Q, Zhang J, Lv Q, Wang P, Lai Z, Wang G, Zheng C, Gong L, Liu Z.   +11 more
europepmc   +1 more source

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

The FEBS Journal, EarlyView.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar, Siarhei Paliavoi, Barbora Stefanovie, Jan Josef Palecek   +3 more
wiley   +1 more source

Post‐transcriptional regulatory networks: The dynamic interplay of RNA‐binding proteins

The FEBS Journal, EarlyView.
Post‐transcriptional gene expression regulation is controlled by RNA‐binding proteins (RBPs), which influence many processes including splicing, localization, translation, and decay. Rather than acting alone, RBPs bind RNAs combinatorially, forming complex, context‐dependent regulatory networks.
Lena A. Street, Marko Jovanovic, Eugenio F. Fornasiero   +2 more
wiley   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source

Unveiling the Silent Regulators: Noncoding RNAs in Parasitic Disease Diagnosis and Therapy. [PDF]

J Parasitol Res
Loku Gamage N, Ranasinghe K.
europepmc   +1 more source

Constitution and function of intergenic genome regions in cultivated versus annual wild soybean in China

Journal of Integrative Plant Biology, EarlyView.
Three‐case restricted two‐stage multi‐locus multi‐allele genome‐wide association study identified main‐effect genes and detected the regulatory effects of intergenic loci on genes, enabling comprehensive dissection of the genic‐intergenic genetic system for quantitative traits and providing a strategy for studying their genetic basis.
Xiaoshuai Hao, Xinyang Hu, Yongpeng Pan, Qi Zhang, Ran Ou, Fenfen Jiang, Fangdong Liu, Jiaoping Zhang, Wubin Wang, Guangnan Xing, Junyi Gai, Jianbo He   +11 more
wiley   +1 more source

Dual Role of Small Noncoding RNA and Hfq in Bacterial DNA Compaction: A New Perspective on Nucleoid Architecture. [PDF]

ACS Omega
Mistygacz G, Mukherjee S, George JE, Wien F, Yadav I, van der Maarel JRC, Arluison V.   +6 more
europepmc   +1 more source

Pangenome analysis reveals the genetic mechanism underlying high‐altitude adaptation in Qinghai–Xizang (Tibet) Plateau Rhododendron

Journal of Integrative Plant Biology, EarlyView.
Pan‐genome analysis reveals that high‐altitude Rhododendron species resist alpine cold stress by rapidly sensing and engaging the chilling response pathway and genes that directly and indirectly protect the plant from UV radiation. Heritable genomic features such as long terminal repeats contribute to the adaptive diversification of Rhododendron ...
Haoyang Zhou, Zhongping Xu, Fanhuang Zeng, Haiyu Sang, Zhenhua Liu, Miao Sun, Qiang Fu, Kaige Zhao, Daming Tan, Manzhu Bao, Shuangxia Jin, Xiuqun Liu   +11 more
wiley   +1 more source

Noncoding RNAs and the phytochemical economy: Molecular regulators of secondary metabolism in medicinal plants. [PDF]

Biochem Biophys Rep
Ugwu OP, Ugwu MN, Onohuean H, Rather HA, Usman IM.   +4 more
europepmc   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source