Results 191 to 200 of about 8,401,372 (300)

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

The FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

Retraction: The Long Noncoding RNA HOTAIR Promotes Colorectal Cancer Progression by Sponging miR-197. [PDF]

Oncol Res
Oncology Research Editorial Office.
europepmc   +1 more source

Epigenetic control of cellular plasticity in breast cancer progression

The FEBS Journal, EarlyView.
Cancer cells undergo cell state transitions, termed plasticity, driving cancer progression and dictating therapeutic response. We define breast cancer plasticity into four interconnected processes: (1) breast cancer stem cell fates, (2) epithelial‐to‐mesenchymal transition, (3) maintenance of luminal identity, and (4) acquisition of therapeutic ...
Ellie J. Massey, Elizabeth Podleszanski, William J. Muller   +2 more
wiley   +1 more source

ELE: Estimating tissue-specific long noncoding RNA gene essentiality using graph neural networks. [PDF]

Quant Biol
Shi WT, Liu YD, Gong XJ, Du PF.
europepmc   +1 more source

The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis

The FEBS Journal, EarlyView.
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo, Evodie Peperstraete, Léa Mabille, Joséphine Louvieaux, Jim Marmuse, Clément Lecerf, Chann Lagadec, Xuefen Le Bourhis, Éric Adriaenssens   +8 more
wiley   +1 more source

A hybrid transcriptome assembly reveals coding and noncoding landscapes in Drosophila hemocytes. [PDF]

Genetics
Lee KT, Cho B, Lee D, Yoon S, Do H, Han J, Na H, Yoon S, Shin M, Shim J, Nam JW.   +10 more
europepmc   +1 more source

Toward a minimal amino acid alphabet for protein design

The FEBS Journal, EarlyView.
Proteins are built from 20 canonical amino acids; however, it is interesting to investigate whether they can also be formed from reduced amino acid alphabets. Using protein design, we designed proteins based on all alphabets comprising 2 to 10 ‘early’ amino acids (those likely to have been present before the origin of life).
Karel Půbal, Kseniia Kushnir, Vojtěch Spiwok, Karolína Loužecká, Vladimír Setnička, Petra Lipovová   +5 more
wiley   +1 more source

Statement of Retraction: Long noncoding RNA BBOX1-AS1 promotes the progression of gastric cancer by regulating the miR-361-3p/Mucin 13 signaling axis. [PDF]

Bioengineered
europepmc   +1 more source

Retraction: Long noncoding RNA-MEG3 contributes to myocardial ischemia-reperfusion injury through suppression of miR-7-5p expression. [PDF]

Biosci Rep
Zou L, Ma X, Lin S, Wu B, Chen Y, Peng C.   +5 more
europepmc   +1 more source

A guide to host genetic determinants of female microbiome composition across distinct anatomical niches

The FEBS Journal, EarlyView.
Host genetic variation in immune regulation and cell signalling genes was associated with microbiome composition across vaginal, gut, oral and skin sites, while associations involving metabolic function, epithelial barrier integrity and hormonal processes were more site‐specific. Overall, our findings indicate that host genetic variation contributes to
Isabella Margaret Davidson, Elham Nikbakht, Hayley O'Neill, Larisa Margaret Haupt, Paul Joseph Dunn   +4 more
wiley   +1 more source