Results 1 to 10 of about 484,088 (306)
Effects of alcohol and PARP inhibition on RNA ribosomal engagement in cortical excitatory neurons [PDF]
Frontiers in Molecular Neuroscience, 2023 We report on the effects of ethanol (EtOH) and Poly (ADP-ribose) polymerase (PARP) inhibition on RNA ribosomal engagement, as a proxy for protein translation, in prefrontal cortical (PFC) pyramidal neurons.
Harish R. Krishnan +10 more
doaj +2 more sources
Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. [PDF]
PLoS ONE, 2014 Intact RNA from exosomes/microvesicles (collectively referred to as microvesicles) has sparked much interest as potential biomarkers for the non-invasive analysis of disease.
Kevin C Miranda +8 more
doaj +6 more sources
Cross-site comparison of ribosomal depletion kits for Illumina RNAseq library construction [PDF]
BMC Genomics, 2018 Background Ribosomal RNA (rRNA) comprises at least 90% of total RNA extracted from mammalian tissue or cell line samples. Informative transcriptional profiling using massively parallel sequencing technologies requires either enrichment of mature poly ...
Zachary T. Herbert +20 more
doaj +3 more sources
Dataset of the transcribed 45S ribosomal RNA sequence of the tree crop “yerba mate” [PDF]
Data in Brief, 2017 This contribution contains data related to the research article entitled “The 18S-25S ribosomal RNA unit of yerba mate (Ilex paraguariensis A. St.-Hil.)” (Aguilera et al., 2016) [1].
Patricia M. Aguilera +2 more
doaj +4 more sources
Evidence for further non-coding RNA genes in the fungal rDNA region [PDF]
MycoKeys, 2022 Non-coding RNA (ncRNA) genes play important, but incompletely understood, roles in various cellular processes, notably translation and gene regulation.
Magnus Alm Rosenblad +5 more
doaj +3 more sources
Frontiers in Ecology and Evolution, 2015 It was Francis Crick who first asked why the ribosome contains so much RNA, and discussed the implications of this for the direct flow of genetic information from DNA to protein. Remarkable advances in our understanding of the ribosome and protein synthesis, including the recent publication of two mammalian mitochondrial ribosome structures, have shed ...
Harold S. Bernhardt, Warren P. Tate
openaire +2 more sources
Varying strength of selection contributes to the intragenomic diversity of rRNA genes
Nature Communications, 2022 Ribosomal RNA genes are abundant in eukaryotic genomes and code for the universal and essential RNA components of the ribosome. This study uncovers high sequence diversity of the genes within a single species and discusses the contribution of selection ...
Daniel Sultanov, Andreas Hochwagen
doaj +1 more source
Ribosomal control in RNA virus-infected cells
Frontiers in Microbiology, 2022 Viruses are strictly intracellular parasites requiring host cellular functions to complete their reproduction cycle involving virus infection of host cell, viral genome replication, viral protein translation, and virion release.
Xiao Wang +3 more
doaj +1 more source
Nature Communications, 2021 Early steps of large 60S ribosomal subunit biogenesis are not well understood. Here, the authors combine biochemical experiments with protein-RNA crosslinking and mass spectrometry to show that the RNA helicase Dbp7 is key player during early 60S ...
Gerald Ryan R. Aquino +9 more
doaj +1 more source
Ribosome Biogenesis in Archaea
Frontiers in Microbiology, 2021 Making ribosomes is a major cellular process essential for the maintenance of functional ribosome homeostasis and to ensure appropriate gene expression.
Paola Londei, Sébastien Ferreira-Cerca
doaj +1 more source