Results 1 to 10 of about 1,583,638 (190)
Effects of alcohol and PARP inhibition on RNA ribosomal engagement in cortical excitatory neurons. [PDF]
Front Mol Neurosci, 2023 We report on the effects of ethanol (EtOH) and Poly (ADP-ribose) polymerase (PARP) inhibition on RNA ribosomal engagement, as a proxy for protein translation, in prefrontal cortical (PFC) pyramidal neurons.
Krishnan HR +6 more
europepmc +2 more sources
Transcription–translation coupling: direct interactions of RNA polymerase with ribosomes and ribosomal subunits [PDF]
Nucleic Acids Research, 2017 In prokaryotes, RNA polymerase and ribosomes can bind concurrently to the same RNA transcript, leading to the functional coupling of transcription and translation.
H. Fan +9 more
semanticscholar +3 more sources
Frontiers in Ecology and Evolution, 2015 It was Francis Crick who first asked why the ribosome contains so much RNA, and discussed the implications of this for the direct flow of genetic information from DNA to protein. Remarkable advances in our understanding of the ribosome and protein synthesis, including the recent publication of two mammalian mitochondrial ribosome structures, have shed ...
Harold S. Bernhardt, Warren P. Tate
openaire +2 more sources
The mitochondrial ribosome and ribosomal RNA of the chick [PDF]
FEBS Letters, 1971 Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Terence H. Rabbitts, T.S. Work
openaire +3 more sources
A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]
, 2010 Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M +2 more
core +3 more sources
The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
Nucleic Acids Res., 2012 SILVA (from Latin silva, forest, http://www.arb-silva.de) is a comprehensive web resource for up to date, quality-controlled databases of aligned ribosomal RNA (rRNA) gene sequences from the Bacteria, Archaea and Eukaryota domains and supplementary ...
Christian Quast +7 more
semanticscholar +1 more source
Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome
Science, 2020 Shifting frames to make more proteins Severe acute respiratory syndrome coronavirus 2 critically depends on the ribosomal frameshifting that occurs between two large open reading frames in its genomic RNA for expression of viral replicase.
P. R. Bhatt +13 more
semanticscholar +1 more source
Homoiterons and expansion in ribosomal RNAs [PDF]
FEBS Open Bio, 2015 Ribosomal RNAs in both prokaryotes and eukaryotes feature numerous repeats of three or more nucleotides with the same nucleobase (homoiterons). In prokaryotes these repeats are much more frequent in thermophile compared to mesophile or psychrophile species, and have similar frequency in both large RNAs.
Steven L. Parker +3 more
openaire +4 more sources
Nucleic Acids Research, 2012 16S ribosomal RNA gene (rDNA) amplicon analysis remains the standard approach for the cultivation-independent investigation of microbial diversity. The accuracy of these analyses depends strongly on the choice of primers.
A. Klindworth +6 more
semanticscholar +1 more source
RNA‐guided nucleotide modification of ribosomal and non‐ribosomal RNAs in Archaea [PDF]
Molecular Microbiology, 2004 SummaryArchaea use ribonucleoprotein (RNP) machines similar to those found in the eukaryotic nucleolus to methylate ribose residues in nascent ribosomal RNA. The archaeal complex required for this 2′‐O‐ribose‐methylation consists of the C/D box sRNA guide and three proteins, the core RNA‐binding aL7a protein, the aNop56 protein and the ...
Patrick P. Dennis +3 more
openaire +3 more sources