Results 1 to 10 of about 487,536 (292)

Effects of alcohol and PARP inhibition on RNA ribosomal engagement in cortical excitatory neurons [PDF]

open access: yesFrontiers in Molecular Neuroscience, 2023
We report on the effects of ethanol (EtOH) and Poly (ADP-ribose) polymerase (PARP) inhibition on RNA ribosomal engagement, as a proxy for protein translation, in prefrontal cortical (PFC) pyramidal neurons.
Harish R. Krishnan   +10 more
doaj   +2 more sources

Evidence for further non-coding RNA genes in the fungal rDNA region [PDF]

open access: yesMycoKeys, 2022
Non-coding RNA (ncRNA) genes play important, but incompletely understood, roles in various cellular processes, notably translation and gene regulation.
Magnus Alm Rosenblad   +5 more
doaj   +3 more sources

Ribosomal control in RNA virus-infected cells

open access: yesFrontiers in Microbiology, 2022
Viruses are strictly intracellular parasites requiring host cellular functions to complete their reproduction cycle involving virus infection of host cell, viral genome replication, viral protein translation, and virion release.
Xiao Wang   +3 more
doaj   +1 more source

A Ribosome Without RNA [PDF]

open access: yesFrontiers in Ecology and Evolution, 2015
It was Francis Crick who first asked why the ribosome contains so much RNA, and discussed the implications of this for the direct flow of genetic information from DNA to protein. Remarkable advances in our understanding of the ribosome and protein synthesis, including the recent publication of two mammalian mitochondrial ribosome structures, have shed ...
Harold S. Bernhardt, Warren P. Tate
openaire   +2 more sources

Varying strength of selection contributes to the intragenomic diversity of rRNA genes

open access: yesNature Communications, 2022
Ribosomal RNA genes are abundant in eukaryotic genomes and code for the universal and essential RNA components of the ribosome. This study uncovers high sequence diversity of the genes within a single species and discusses the contribution of selection ...
Daniel Sultanov, Andreas Hochwagen
doaj   +1 more source

The RNA helicase Dbp7 promotes domain V/VI compaction and stabilization of inter-domain interactions during early 60S assembly

open access: yesNature Communications, 2021
Early steps of large 60S ribosomal subunit biogenesis are not well understood. Here, the authors combine biochemical experiments with protein-RNA crosslinking and mass spectrometry to show that the RNA helicase Dbp7 is key player during early 60S ...
Gerald Ryan R. Aquino   +9 more
doaj   +1 more source

Ribosome Biogenesis in Archaea

open access: yesFrontiers in Microbiology, 2021
Making ribosomes is a major cellular process essential for the maintenance of functional ribosome homeostasis and to ensure appropriate gene expression.
Paola Londei, Sébastien Ferreira-Cerca
doaj   +1 more source

The mitochondrial ribosome and ribosomal RNA of the chick [PDF]

open access: yesFEBS Letters, 1971
Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Terence H. Rabbitts, T.S. Work
openaire   +3 more sources

Epitranscriptomics of Mammalian Mitochondrial Ribosomal RNA

open access: yesCells, 2020
Modified nucleotides are present in all ribosomal RNA molecules. Mitochondrial ribosomes are unique to have a set of methylated residues that includes universally conserved ones, those that could be found either in bacterial or in archaeal/eukaryotic ...
Ivan Laptev, Olga Dontsova, Petr Sergiev
doaj   +1 more source

Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. [PDF]

open access: yesPLoS ONE, 2014
Intact RNA from exosomes/microvesicles (collectively referred to as microvesicles) has sparked much interest as potential biomarkers for the non-invasive analysis of disease.
Kevin C Miranda   +8 more
doaj   +1 more source

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