Results 1 to 10 of about 1,552,252 (271)
Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation
Nature Communications, 2016 Ribosome biogenesis involves the hierarchical assembly of several proteins and RNA components. Here the authors describe a mechanism for ribosomal protein S3 incorporation into 40S ribosomal subunits that involves S3 dimerization and stepwise ...
Valentin Mitterer +9 more
doaj +1 more source
eLife, 2018 Ribosome degradation through the autophagy-lysosome pathway is crucial for cell survival during nutrient starvation, but whether it occurs under normal growth conditions and contributes to animal physiology remains unaddressed.
Yubing Liu +6 more
doaj +1 more source
Nature Communications, 2016 Circular RNAs (circRNAs) represent a class of widespread and diverse endogenous RNAs that may regulate gene expression in eukaryotes. However, the regulation and function of human circRNAs remain largely unknown.
Qiupeng Zheng +13 more
semanticscholar +1 more source
Size, shape, and flexibility of RNA structures
, 2006 Determination of sizes and flexibilities of RNA molecules is important in understanding the nature of packing in folded structures and in elucidating interactions between RNA and DNA or proteins.
Cantor C. R. +4 more
core +1 more source
Biomolecules, 2018 Ribosomal RNA (rRNA) is extensively edited through base methylation and acetylation, 2′-O-ribose methylation and uridine isomerization. In human rRNA, 95 uridines are predicted to by modified to pseudouridine by ribonucleoprotein complexes sharing ...
Marianna Penzo, Lorenzo Montanaro
doaj +1 more source
The unknotted strands of life: knots are very rare in RNA structures [PDF]
arXiv, 2014 The ongoing effort to detect and characterize physical entanglement in biopolymers has so far established that knots are present in many globular proteins and also abound in viral DNA packaged inside bacteriophages. RNA molecules, on the other hand, have not yet been systematically screened for the occurrence of physical knots.
arxiv
Function of Plant DExD/H-Box RNA Helicases Associated with Ribosomal RNA Biogenesis
Frontiers in Plant Science, 2018 Ribosome biogenesis is a highly complex process that requires several cofactors, including DExD/H-box RNA helicases (RHs). RHs are a family of ATPases that rearrange the secondary structures of RNA and thus remodel ribonucleoprotein complexes. DExD/H-box
Yuelin Liu, Ryozo Imai
doaj +1 more source
Identification of the prebiotic translation apparatus within the contemporary ribosome [PDF]
, 2009 A structural element that could have existed independently in the prebiotic era was identified at the active site of the contemporary ribosome. It is suggested to have functioned as a proto-ribosome catalyzing peptide bond formation and non-coded ...
Ada Yonath +3 more
core +1 more source
A Unifying Scenario on the Origin and Evolution of Cellular and Viral Domains [PDF]
, 2009 The cellular theory on the nature of life has been one of the first major advancements in biology. Viruses, however, are the most abundant life forms, and their exclusion from mainstream biology and the Tree of Life (TOL) is a major paradox in biology ...
Claudiu I. Bandea
core +1 more source