Results 111 to 120 of about 547,696 (232)
Biogenesis and regulatory hierarchy of phased small interfering RNAs in plants
Plant Biotechnology Journal, 2018 Summary Several varieties of small RNAs including microRNAs (miRNAs) and small interfering RNAs (siRNAs) are generated in plants to regulate development, genome stability and response to adverse environments.
Pingchuan Deng +3 more
semanticscholar +1 more source
مجله دانشکده پزشکی اصفهان, 2017 Background: Eukaryotic cells have membrane organelles. Due to the high prevalence of toxoplasmosis and lack of effective drugs especially on dormant cystic stages, we aimed adding small interfering RNA (siRNA) in culture medium on the proliferation ...
Abbas Ali Eskandarian +1 more
doaj
Decrease in gyrase A protein expression in _E. coli_ cells inhibited by antisense ribozymes [PDF]
, 2008 RNase P complexed with external guide sequence (EGS) represents a novel nucleic-acid-based gene interference approach to modulate gene expression. Nucleic acid-based gene interference technologies represent promising strategies for specific inhibition of
Malathi Raghunathan +1 more
core +1 more source
Viral RNA recognition by the Drosophila small interfering RNA pathway
Microbes and Infection, 2014 Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.
Soares, Zamira Guerra +3 more
openaire +3 more sources
Neoplasia, 2011 RNA interference holds tremendous potential as a therapeutic approach, especially in the treatment of malignant tumors. However, efficient and biocompatible delivery methods are needed for systemic delivery of small interfering RNA (siRNA). To maintain a
M. Shahzad +23 more
semanticscholar +1 more source
Small Interfering RNA Targeting Nerve Growth Factor Alleviates Allergic Airway Hyperresponsiveness
Molecular Therapy: Nucleic Acids, 2014 Airway hyperresponsiveness is the hallmark of allergic asthma and caused by multiple factors. Nerve growth factor (NGF), a neurotrophin, is originally known for regulation of neural circuit development and function.
Yi-Lien Chen +3 more
doaj +1 more source
Molecular Medicine Reports, 2017 Aquaporin 3 (AQP3) and phospholipase D2 (PLD2) are abnormally expressed and/or localized in squamous cell carcinoma (SCC). AQP3 transports glycerol to PLD2 for the synthesis of lipid second messenger, which can mediate the effect of the AQP3/PLD2 signaling module in the regulation of keratinocyte proliferation and differentiation.
Hangyu Ying +5 more
openaire +4 more sources
Small interfering RNA for cancer treatment: overcoming hurdles in delivery
Acta Pharmaceutica Sinica B, 2020 Nitin B. Charbe +18 more
semanticscholar +1 more source
siARN e shARN: aspectos básicos e aplicados : seu uso como agentes terapêuticos [PDF]
, 2011 La interferencia del ARN es un fenómeno por el cual pequeñas moléculas de ARN doble cadena inhiben la expresión génica de manera secuencia específica. Esta vía se encuentra altamente conservada en los organismos eucariotas.
Baldi, Alberto +5 more
core
Intramyocardial gene silencing by interfering RNA [PDF]
, 2017 RNAi is a widely used methodology for gene silencing. The action mechanism of siRNA molecules has been well studiedin recent years, and the technique has been optimized in terms of safety and effectiveness. Cardiovascular diseases havea high incidence in
Brea, María Soledad +2 more
core +1 more source