Results 251 to 260 of about 348,149 (303)

RNA-Based Therapies for Inherited Metabolic Disorders. [PDF]

J Inherit Metab Dis
Vootukuri RS, Gurung S, Ghosh R, Mills PB, Baruteau J, Zhou H.   +5 more
europepmc   +1 more source

LINC00473 modulates protein expression to promote ovarian cancer progression and overcome cisplatin resistance. [PDF]

Oncol Lett
Zhang C, Ma J, Wang W, Guo M, Han C, Sadike M, Zhu K.   +6 more
europepmc   +1 more source

Cholesterol-dependent control of endosomal escape regulates intracellular trafficking of small interfering RNA therapeutics and interactions with small molecule drugs. [PDF]

J Pharmacol Exp Ther
Tawfik SM, Giang Nguyen LT, Jin J, Armanios B, Zhong XB.   +4 more
europepmc   +1 more source

RNA G-quadruplexes in oncogene regulation and as emerging targets for cancer therapy. [PDF]

Cell Commun Signal
Liu ZY, Wang XY, Gong DD, Tang X, Man CF, Zhang SQ, Fan Y.   +6 more
europepmc   +1 more source

STAT1 accelerates cutaneous melanoma progression through TUBB4A expression regulation. [PDF]

Mol Med Rep
Zhao R, Fang K, Zhang X, Li H.
europepmc   +1 more source

Estrogen receptor (ESR) 1 promotes uterine leiomyoma cell proliferation by enhancing mitochondrial energy metabolism via Wnt/β-catenin pathway activation. [PDF]

BMC Womens Health
Wu Q, Bai S, Duan X, Song L, Han L, Guo Q.   +5 more
europepmc   +1 more source

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Small interfering RNAs target HIV

The Lancet, 2003
openaire   +3 more sources

Small interfering RNA (siRNA)-based therapeutics

Drug and Therapeutics Bulletin, 2023
In early studies in simple organisms and mammalian cell lines, small interfering RNA (siRNA) molecules were found to allow experimental cleavage of intracellular messenger RNA (mRNA; the transcription product of a cell gene), reducing the levels of the proteins that would otherwise be formed by the action of the mRNA, thereby ‘silencing’ a specific ...
openaire   +2 more sources