Results 201 to 210 of about 903,775 (310)
This study presents a novel platform for assessing the active mechanical behavior of living cardiac microbundles through localized nanoindentation, integrated with temperature regulation and dual‐camera imaging systems. The developed system enables quantitative evaluation of dynamic micromechanics in engineered cardiac tissues in vitro, offering ...
Lihua Lou +4 more
wiley +1 more source
Decoding Argonaute specificity: insights from <i>C. elegans</i> and beyond. [PDF]
Chen S, Phillips CM.
europepmc +1 more source
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
The nuclear cap-binding complex regulates subcellular RNA processing and surveillance of coding and noncoding RNAs. [PDF]
Ganguly DR, Gregory BD.
europepmc +1 more source
Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices
Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen +11 more
wiley +1 more source
Overexpression of ACTL6A is associated with poor prognosis in gastric cancer, and nuclear level is an independent predictor. [PDF]
Wang Q, He H, Zhou Y, Li P, Huang T.
europepmc +1 more source
Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Noncoding RNAs are indispensable architects and regulators of biomolecular condensates. [PDF]
Chen S +5 more
europepmc +1 more source
We demonstrated that high humidity worsened psoriasis relapse in murine psoriasiform skin inflammation by increasing skin‐resident memory CD8+ cells via upregulating IL‐15Rα on keratinocytes. The increases in IL‐15Rα and memory CD8+ cells were attributed to S. nepalensis and its metabolite ADMA in skin exposed to high humidity.
Chun‐Ling Liang +10 more
wiley +1 more source

