Results 61 to 70 of about 498,663 (149)

sRNAPipe: a Galaxy-based pipeline for bioinformatic in-depth exploration of small RNAseq data

open access: yesMobile DNA, 2018
Background The field of small RNA is one of the most investigated research areas since they were shown to regulate transposable elements and gene expression and play essential roles in fundamental biological processes. Small RNA deep sequencing (sRNA-seq)
Romain Pogorelcnik   +4 more
doaj   +1 more source

Multiple pseudouridine synthase activities for small nuclear RNAs [PDF]

open access: yesBiochemical Journal, 1993
The formation of pseudouridine (psi) in human U1, U2 and U5 small nuclear RNAs (snRNAs) was investigated using HeLa cell extracts. Unmodified snRNAs were synthesized in vitro and the extent of psi formation was determined after incubation in cell extracts. The formation of psi on labelled substrates was monitored in the presence of 5-fluorouracil (5-FU)
openaire   +3 more sources

Molecular principles underlying dual RNA specificity in the Drosophila SNF protein

open access: yesNature Communications, 2018
It remains poorly understood how a single RNA-binding protein recognizes diverse RNA targets. Here the authors use an integrative approach to study the binding of spliceosomal SNF protein to U1 and U2 small nuclear RNAs in the presence or absence of ...
Gert Weber   +4 more
doaj   +1 more source

RNAs as Proximity-Labeling Media for Identifying Nuclear Speckle Positions Relative to the Genome

open access: yesiScience, 2018
Summary: It remains challenging to identify all parts of the nuclear genome that are in proximity to nuclear speckles, due to physical separation between the nuclear speckle cores and chromatin. We hypothesized that noncoding RNAs including small nuclear
Weizhong Chen   +6 more
doaj  

Morphological characters and molecular data reveal ten new forest macrofungi species from Hebei Province, North China

open access: yesMycology
China has a complex and diverse forest ecological environment, which breeds abundant forest macrofungi, including some edible, medicinal, and poisonous species. During the investigations of macrofungi in the Saihanba National Nature Reserve, North China,
Shun Liu, Bao-Kai Cui, Biao Zhu
doaj   +1 more source

Dual RNA Processing Roles of Pat1b via Cytoplasmic Lsm1-7 and Nuclear Lsm2-8 Complexes

open access: yesCell Reports, 2017
Summary: Pat1 RNA-binding proteins, enriched in processing bodies (P bodies), are key players in cytoplasmic 5′ to 3′ mRNA decay, activating decapping of mRNA in complex with the Lsm1-7 heptamer.
Caroline Vindry   +10 more
doaj  

Multi-omics analysis using antibody-based in situ biotinylation technique suggests the mechanism of Cajal body formation

open access: yesCell Reports
Summary: Membrane-less subcellular compartments play important roles in various cellular functions. Although techniques exist to identify components of cellular bodies, a comprehensive method for analyzing both static and dynamic states has not been ...
Keisuke Noguchi   +17 more
doaj  

Small Nuclear Ribonucleoprotein Autoantibody Associated With Blood-Nerve Barrier Breakdown in Guillain-Barré Syndrome. [PDF]

open access: yesNeurol Neuroimmunol Neuroinflamm
Shimizu F   +8 more
europepmc   +1 more source

Liquid-liquid phase separation of membrane-less condensates: from biogenesis to function. [PDF]

open access: yesFront Cell Dev Biol
Guan H   +11 more
europepmc   +1 more source

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