Results 61 to 70 of about 903,775 (310)
Low-energy neutrino physics and neutrino mass [PDF]
, 1984 Among the principal concerns in neutrino physics today are the questions of whether neutrinos are massive and, if so, whether the neutrinos emitted in a weak decay are pure or mixed quantum states. The concept of mixed neutrinos has been with us for more
Boehm, F., Vogel, P.
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Circadian control of interferon-sensitive gene expression in murine skin. [PDF]
, 2020 The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi +9 more
core +2 more sources
Transcriptional signals of a U4 small nuclear RNA gene [PDF]
Nucleic Acids Research, 1987 The signals controlling the expression of a chicken U4 small nuclear RNA (snRNA) gene have been studied by microinjection into Xenopus oocytes. At least two distinct regions in the 5'-flanking DNA contribute to U4B RNA gene expression. The proximal regulatory element, which is inactivated by a 5'-flanking DNA deletion to position -38, provides a basal ...
K J, McNamara +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Conjoined use of EM and NMR in RNA structure refinement. [PDF]
PLoS ONE, 2015 More than 40% of the RNA structures have been determined using nuclear magnetic resonance (NMR) technique. NMR mainly provides local structural information of protons and works most effectively on relatively small biomacromolecules.
Zhou Gong +2 more
doaj +1 more source
Plants, 2023 Angiosperms form the largest phylum within the Plantae kingdom and show remarkable genetic variation due to the considerable difference in the nuclear genome size of each species.
Joseph L. Pegler +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Decoding m6Am by simultaneous transcription-start mapping and methylation quantification
eLifeN 6,2’-O-dimethyladenosine (m6Am) is a modified nucleotide located at the first transcribed position in mRNA and snRNA that is essential for diverse physiological processes. m6Am mapping methods assume each gene uses a single start nucleotide.
Jianheng Fox Liu +3 more
doaj +1 more source
Nuclear pore complex protein mediated nuclear localization of dicer protein in human cells.
PLoS ONE, 2011 Human DICER1 protein cleaves double-stranded RNA into small sizes, a crucial step in production of single-stranded RNAs which are mediating factors of cytoplasmic RNA interference. Here, we clearly demonstrate that human DICER1 protein localizes not only
Yoshinari Ando +14 more
doaj +1 more source