Results 261 to 270 of about 218,333 (309)

Development of Entebbe Bat Virus Reverse Genetics System and Phenotypic Evaluation of Rescued Virus Reveals Host-Specific Replication Patterns in Mosquitoes. [PDF]

Am J Trop Med Hyg
Fujii M, Gallichotte EN, Sanchez-Vargas I, Enney BM, Malsick LE, Ebel GD, Geiss BJ.   +6 more
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

HIV-1 infection regulates gene expression by altering alternative polyadenylation correlated with CPSF6 and CPSF5 redistribution. [PDF]

mBio
Luchsinger C, Dai AZ, Yalamanchili H, Balakrishnan A, Huang K-L, Bertelli C, Cui B, Lorenzo-Redondo R, Wagner EJ, Diaz-Griffero F.   +9 more
europepmc   +1 more source

The complexities of respiratory chain biogenesis and maintenance in yeast mitochondria

Protein Science, Volume 35, Issue 4, April 2026.
Abstract Mitochondrial oxidative phosphorylation is the most efficient way of energy conversion for eukaryotic cells. It is executed by a series of high‐molecular weight enzyme complexes in the inner mitochondrial membrane that were acquired during endosymbiosis at the root of eukaryotic evolution.
Andreas Carlström, Carmela Vazquez‐Calvo, Martin Ott   +2 more
wiley   +1 more source

A rare 5'UTR variant in SEC24D reveals translational dysfunction in osteogenesis imperfecta: a roadmap for RNA therapeutic rescue. [PDF]

Sci Rep
Essawi O, Jarayseh T, Tapaneeyaphan P, Bouckaert M, Naessens S, Malfait F, Coppieters F, Coucke PJ.   +7 more
europepmc   +1 more source

Engineering Yeast Extracellular Vesicle Biogenesis Through Rewiring Membrane Trafficking Pathways

Microbial Biotechnology, Volume 19, Issue 4, April 2026.
Engineered Saccharomyces cerevisiae reveals how cell wall remodelling and membrane trafficking coordinate extracellular vesicle biogenesis. Interferon overexpression and chs3 deletion enhance EV secretion and reshape SNARE‐, Rab‐ and ESCRT‐associated pathways, establishing yeast as a versatile platform for EV engineering and therapeutic cargo loading ...
Yueyan Li, XiaoRan Ma, Lichao Zhang, Ning Cao, Zhibo Li, Ruixin Khoo, Mei Wang, Changyan Li, Deping Hua, Xintian Zheng, Jinhai Huang, Lilin Zhang   +11 more
wiley   +1 more source

The Cap-Independent Translation of Survivin 5'UTR and HIV-1 IRES Sequences Is Inhibited by Oxidative Stress Produced by <i>H. pylori</i> Gamma-Glutamyl Transpeptidase Activity. [PDF]

Biomolecules
Rubilar M, Carrasco-Véliz N, Garrido MP, Silva MI, Quest AFG, González MF, Palacios E, Villena J, Montenegro I, Valenzuela-Valderrama M.   +9 more
europepmc   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

UTR-DynaPro: a CNN-transformer multimodal language model for decoding 5'UTR regulatory mechanisms. [PDF]

Sci Rep
Shen H, Liu S, Guo F, Zhu J, Meng J, Chen J.   +5 more
europepmc   +1 more source

Development of the reverse genetics system for viral hemorrhagic septicemia virus genotype IVa and its application in antiviral compound screening. [PDF]

Virol Sin
Huang H, Lu X, Hong T, Chen Y, Yi M, Jia K.   +5 more
europepmc   +1 more source