Results 71 to 80 of about 1,114,234 (207)
Effect of dsRNA on Mesangial Cell Synthesis of Plasminogen Activator Inhibitor Type 1 and Tissue Plasminogen Activator [PDF]
, 2009 Background/Aims: Viral infections are a major problem worldwide and many of them are complicated by virally induced glomerulonephritides. Progression of kidney disease to renal failure is mainly attributed to the development of renal fibrosis ...
Merkle, Monika +4 more
core +1 more source
Molecular Bases of Viral RNA Targeting by Viral Small Interfering RNA-Programmed RISC [PDF]
Journal of Virology, 2007 ABSTRACT RNA silencing is conserved in a broad range of eukaryotes and operates in the development and maintenance of genome integrity in many organisms. Plants have adapted this system for antiviral defense, and plant viruses have in turn developed mechanisms to suppress RNA silencing.
Pantaleo, V., Szittya, G., Burgyán, J.
openaire +3 more sources
Ribosomal frameshifting on viral RNAs
Journal of General Virology, 1995 Introduction. Accurate maintenance of the translational reading frame by ribosomes is essential for the production of functional proteins and unsurprisingly, errors in frame maintenance have been estimated to occur at rates probably lower than 5 × 10-5 per codon (Kurland, 1992).
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Icosahedral Packing of RNA Viral Genomes [PDF]
Physical Review Letters, 2005 4 pages revtex, 4 eps ...
Rudnick, Joseph, Bruinsma, Robijn
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Mycoviruses, RNA Silencing, and Viral RNA Recombination [PDF]
, 2011 In contrast to viruses of plants and animals, viruses of fungi, mycoviruses, uniformly lack an extracellular phase to their replication cycle. The persistent, intracellular nature of the mycovirus life cycle presents technical challenges to experimental design. However, these properties, coupled with the relative simplicity and evolutionary position of
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Nature Communications, 2021 N6-methyladenosine (m6A) RNA modification regulates RNA metabolism, and has been implicated in immune regulation. Here, the authors show that the m6A methyltransferase, METTL3, translocates into the cytoplasm to increase viral RNA m6A modification ...
Weinan Qiu +17 more
doaj +1 more source
The respiratory syncytial virus nucleoprotein–RNA complex forms a left-handed helical nucleocapsid [PDF]
, 2013 Respiratory Syncytial Virus (RSV) is an important human pathogen. Its nucleocapsid (NC), which comprises the negative sense RNA viral genome coated by the viral nucleoprotein N, is a critical assembly that serves as template for both mRNA synthesis and ...
Bhella +10 more
core +3 more sources
PLoS Pathogens, 2017 RNA viruses encode various RNA binding proteins that function in many steps of viral infection cycles. These proteins function as RNA helicases, methyltransferases, RNA-dependent RNA polymerases, RNA silencing suppressors, RNA chaperones, movement ...
Kun Zhang +8 more
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PAN RNA: transcriptional exhaust from a viral engine
Journal of Biomedical Science, 2020 Kaposi’s sarcoma-associated herpesvirus (KSHV), also designated human herpesvirus 8 (HHV-8), has been linked to Kaposi’s sarcoma, as well as to primary effusion lymphoma (PEL), and a subset of multicentric Castleman’s disease. KSHV genomes are maintained
Mel Campbell, Yoshihiro Izumiya
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Rapid whole genome sequencing methods for RNA viruses
Frontiers in Microbiology, 2023 RNA viruses are the etiological agents of many infectious diseases. Since RNA viruses are error-prone during genome replication, rapid, accurate and economical whole RNA viral genome sequence determination is highly demanded.
Masayasu Misu +10 more
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