Results 61 to 70 of about 2,102,458 (307)

Influence of viral genes on the cell-to-cell spread of RNA silencing [PDF]

The turnip crinkle virus-based vector TCV–GFPDCP had been devised previously to study cell-to-cell and long-distance spread of virus-induced RNA silencing.
Hong, Yiguo, Zhou, Yu, Ryabov, Eugene V., Zhang, Xuemei   +3 more
core   +1 more source

Defense pathways in Arabidopsis restricting compatible tobamoviruses during infection [PDF]

, 2014
Virus infected plants often develop strong disease symptoms including leaf deformation, chlorosis, necrosis and growth inhibition. In agriculture systems virus infection can lead to severe yield losses and a better understanding of plant defenses against
Kørner, Camilla Julie
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Nucleocapsid protein captures DDX5 and RNMT facilitating viral RNA synthesis and viral protein translation for coronavirus replication

mBio
Coronaviruses (CoVs) hijack host RNA-binding proteins (RBPs) to facilitate their replication, but the viral proteins and host RBDs that participate in the synthesis of viral RNA and protein are unclear.
Yuchang Liu, Ning Kong, Xinyu Yang, Wenzhen Qin, Yahe Wang, Chen Wang, He Sun, Jiarui Wang, Ao Gao, Dongfang Zheng, Wu Tong, Hai Yu, Hao Zheng, Guangzhi Tong, Tongling Shan   +14 more
doaj   +1 more source

Structures and Functions of Viral 5′ Non-Coding Genomic RNA Domain-I in Group-B Enterovirus Infections

Viruses, 2020
Group-B enteroviruses (EV-B) are ubiquitous naked single-stranded positive RNA viral pathogens that are responsible for common acute or persistent human infections.
Marie Glenet, Laetitia Heng, Domitille Callon, Anne-Laure Lebreil, Paul-Antoine Gretteau, Yohan Nguyen, Fatma Berri, Laurent Andreoletti   +7 more
doaj   +1 more source

Protein expression redirects vesicular stomatitis virus RNA synthesis to cytoplasmic inclusions. [PDF]

PLoS Pathogens, 2010
Positive-strand and double-strand RNA viruses typically compartmentalize their replication machinery in infected cells. This is thought to shield viral RNA from detection by innate immune sensors and favor RNA synthesis. The picture for the non-segmented
Bianca S Heinrich, David K Cureton, Amal A Rahmeh, Sean P J Whelan   +3 more
doaj   +1 more source

RNA-based viral vectors

Expert Review of Vaccines, 2014
The advent of reverse genetic approaches to manipulate the genomes of both positive (+) and negative (-) sense RNA viruses allowed researchers to harness these genomes for basic research. Manipulation of positive sense RNA virus genomes occurred first largely because infectious RNA could be transcribed directly from cDNA versions of the RNA genomes ...
Mark A, Mogler, Kurt I, Kamrud
openaire   +2 more sources

Molecular Bases of Viral RNA Targeting by Viral Small Interfering RNA-Programmed RISC [PDF]

Journal of Virology, 2007
ABSTRACT RNA silencing is conserved in a broad range of eukaryotes and operates in the development and maintenance of genome integrity in many organisms. Plants have adapted this system for antiviral defense, and plant viruses have in turn developed mechanisms to suppress RNA silencing.
Pantaleo, V., Szittya, G., Burgyán, J.
openaire   +3 more sources

Bluetongue virus non-structural protein 1 is a positive regulator of viral protein synthesis. [PDF]

, 2012
BACKGROUND: Bluetongue virus (BTV) is a double-stranded RNA (dsRNA) virus of the Reoviridae family, which encodes its genes in ten linear dsRNA segments.
Roy Polly, Boyce, Mark, Roy, Polly, Celma, Cristina CP, Cristina C P Celma, Boyce Mark, Mark Boyce, Polly Roy, Celma Cristina C P   +8 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source