Results 41 to 50 of about 2,786,263 (356)

Novel insights into endogenous RNA viral elements in Ixodes scapularis and other arbovirus vector genomes

open access: yesVirus Evolution, 2019
Many emerging arboviruses are not transmitted by traditional mosquito vectors, but by lesser-studied arthropods such as ticks, midges, and sand flies. Small RNA (sRNA) silencing pathways are the main antiviral defence mechanism for arthropods, which lack
Alice G. Russo   +4 more
semanticscholar   +1 more source

RdRp (RNA-dependent RNA polymerase): A key target providing anti-virals for the management of various viral diseases

open access: yesJournal of Molecular Structure, 2021
With the arrival of the Covid-19 pandemic, anti-viral agents have regained center stage in the arena of medicine. Out of the various drug targets involved in managing RNA-viral infections, the one that dominates almost all RNA viruses is RdRp (RNA ...
S. Pathania, R. Rawal, P. Singh
semanticscholar   +1 more source

Next generation sequencing for studying viruses and RNA silencing-based antiviral defense in crop plants [PDF]

open access: yes, 2014
The main objectives of this work have been to use next generation sequencing (NGS) and develop bioinformatics tools for plant virus diagnostics and genome reconstruction as well as for investigation of RNA silencing-based antiviral defense.
Seguin, Jonathan
core   +1 more source

Functional RNA Elements in the Dengue Virus Genome

open access: yesViruses, 2011
Dengue virus (DENV) genome amplification is a process that involves the viral RNA, cellular and viral proteins, and a complex architecture of cellular membranes.
Andrea V. Gamarnik   +2 more
doaj   +1 more source

Prolonged presence of SARS-CoV-2 viral RNA in faecal samples

open access: yesThe Lancet Gastroenterology and Hepatology, 2020
We present severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) real-time RT-PCR results of all respiratory and faecal samples from patients with coronavirus disease 2019 (COVID-19) at the Fifth Affiliated Hospital of Sun Yat-sen University ...
Yongjian Wu   +16 more
semanticscholar   +1 more source

Completion of RNA synthesis by viral RNA replicases [PDF]

open access: yesNucleic Acids Research, 2001
How the 5'-terminus of the template affects RNA synthesis by viral RNA replicases is poorly understood. Using short DNA, RNA and RNA-DNA chimeric templates that can direct synthesis of replicase products, we found that DNA templates tend to direct the synthesis of RNA products that are shorter by 1 nt in comparison to RNA templates. Template-length RNA
R, Tayon , M J, Kim, C C, Kao
openaire   +2 more sources

An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing [PDF]

open access: yes, 2013
Characterisation of RNA and its intermolecular interactions is increasing in importance as the inventory of known RNA functions continues to expand. RNA-RNA interactions are central to post-transcriptional gene regulation mechanisms in bacteria, and the ...
Darren M. Gowers (485354)   +29 more
core   +1 more source

Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. [PDF]

open access: yes, 2014
Bluetongue virus (BTV), a member of the Orbivirus genus within the Reoviridae family, has a genome of 10 double-stranded RNA segments, with three distinct size classes.
Roy, Polly   +3 more
core   +1 more source

Seasonal dynamics of DNA and RNA viral bioaerosol communities in a daycare center

open access: yesMicrobiome, 2019
Viruses play an important role in ecosystems, including the built environment (BE). While numerous studies have characterized bacterial and fungal microbiomes in the BE, few have focused on the viral microbiome (virome).
A. Prussin   +6 more
semanticscholar   +1 more source

Roles of the linker region of RNA helicase A in HIV-1 RNA metabolism. [PDF]

open access: yesPLoS ONE, 2013
RNA helicase A (RHA) promotes multiple steps in HIV-1 production including transcription and translation of viral RNA, annealing of primer tRNA(Lys3) to viral RNA, and elevating the ratio of unspliced to spliced viral RNA.
Li Xing   +3 more
doaj   +1 more source

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