Nucleocapsid Structure of Negative Strand RNA Virus
Viruses, 2020 Negative strand RNA viruses (NSVs) include many important human pathogens, such as influenza virus, Ebola virus, and rabies virus. One of the unique characteristics that NSVs share is the assembly of the nucleocapsid and its role in viral RNA synthesis ...
Ming Luo +2 more
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Activation of influenza virus RNA polymerase by the 5' and 3' terminal duplex of genomic RNA [PDF]
, 2003 The current model for influenza virus mRNA transcription involves the sequential interaction of the viral polymerase with the 5'- and 3'-ends of vRNA, with each RNA-protein interaction triggering a polymerase function necessary for cap-primed ...
Tiley, Laurence +4 more
core +2 more sources
Viral suppression of RNA silencing [PDF]
Science China Life Sciences, 2012 يلعب إسكات الجينات (إسكات الحمض النووي الريبي) دورًا أساسيًا في الدفاع المضاد للفيروسات في النباتات والفطريات واللافقاريات. تقوم الفيروسات بتشفير البروتينات التي تمنع إسكات الجينات لمواجهة دفاع المضيف. تم تحديد المثبطات الفيروسية لإسكات الحمض النووي الريبي (RSVs) من جميع الفيروسات النباتية تقريبًا التي تولد وبعض فيروسات الحشرات والثدييات. كشفت الدراسات
Lin Jiang, Chunhong Wei, Yang Li
openaire +2 more sources
The influence of viral RNA secondary structure on interactions with innate host cell defences [PDF]
, 2013 RNA viruses infecting vertebrates differ fundamentally in their ability to establish persistent infections with markedly different patterns of transmission, disease mechanisms and evolutionary relationships with their hosts.
Blundell, Richard +14 more
core +1 more source
Perspectives on Viral RNA Genomes and the RNA Folding Problem
Viruses, 2020 Viral RNA genomes change shape as virus particles disassemble, form replication complexes, attach to ribosomes for translation, evade host defense mechanisms, and assemble new virus particles.
Susan J. Schroeder
doaj +1 more source
Molecular basis of specific viral RNA recognition and 5′-end capping by the Chikungunya virus nsP1
Cell Reports, 2022 Summary: Many viruses encode RNA-modifying enzymes to edit the 5′ end of viral RNA to mimic the cellular mRNA for effective protein translation, genome replication, and evasion of the host defense mechanisms.
Kuo Zhang +7 more
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Regulation of RNA Virus Processes by Viral Genome Structure
Proceedings, 2020 The genomes of RNA viruses contain a variety of RNA sequences and structures that regulate different steps in virus reproduction. Events that are controlled by RNA elements include (i) the translation of viral proteins, (ii) the replication of viral RNA ...
K. Andrew White
doaj +1 more source
Generation and characterization of a recombinant Rift Valley fever virus expressing a V5 epitope-tagged RNA-dependent RNA polymerase [PDF]
, 2011 The viral RNA-dependent RNA polymerase (RdRp; L protein) of Rift Valley fever virus (RVFV; family Bunyaviridae) is a 238 kDa protein that is crucial for the life cycle of the virus, as it catalyses both transcription of viral mRNAs and replication of the
Brennan, Benjamin +5 more
core +1 more source
RNA Silencing and Plant Viral Diseases
Molecular Plant-Microbe Interactions, 2012 RNA silencing plays a critical role in plant resistance against viruses, with multiple silencing factors participating in antiviral defense. Both RNA and DNA viruses are targeted by the small RNA-directed RNA degradation pathway, with DNA viruses being ...
Ming-Bo Wang +3 more
doaj +1 more source
Coalescence of the sites of cowpea mosaic virus RNA replication into a cytopathic structure [PDF]
, 2002 Cowpea mosaic virus (CPMV) replication induces an extensive proliferation of endoplasmic reticulum (ER) membranes, leading to the formation of small membranous vesicles where viral RNA replication takes place.
Carette, J.E. +3 more
core +1 more source