Results 21 to 30 of about 2,102,458 (307)
Viral sensing by RNA helicases
Virologie, 2020 A key aspect of antiviral immunity is the distinction between "self" and "non-self" components. This distinction can be established through the detection of double-stranded RNA (dsRNA), a common sign of viral infection, by cytosolic RNA helicases.
Rousseau, Claire, Meignin, Carine
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Viral RNA as a Branched Polymer
, 2023 24 pages, 9 ...
Vaupotič, Domen +4 more
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Poly(rC)-Binding Protein 1 Limits Hepatitis C Virus Virion Assembly and Secretion
Viruses, 2022 The hepatitis C virus (HCV) co-opts numerous cellular elements, including proteins, lipids, and microRNAs, to complete its viral life cycle. The cellular RNA-binding protein, poly(rC)-binding protein 1 (PCBP1), was previously reported to bind to the 5 ...
Sophie E. Cousineau +2 more
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A discontinuous RNA platform mediates RNA virus replication: building an integrated model for RNA-based regulation of viral processes. [PDF]
PLoS Pathogens, 2009 Plus-strand RNA viruses contain RNA elements within their genomes that mediate a variety of fundamental viral processes. The traditional view of these elements is that of local RNA structures.
Baodong Wu +5 more
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mBio, 2021 Viral infections have a large impact on society, leading to major human and economic losses and even global instability. So far, many viral infections, including human cytomegalovirus (HCMV) infection, are treated with a small repertoire of drugs, often ...
Ana Cristina Gonzalez-Perez +14 more
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Uirusu, 2009 Many lines of recent evidence indicate that non-coding RNAs including micro RNAs (miRNAs) and small interfering RNAs (siRNAs) play an important role in the control of gene expression in diverse cellular processes and in defense responses against molecular parasites such as viruses and transposons.
IWAKAWA, Hiro-oki, OKUNO, Testuro
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Activation of the interferon induction cascade by influenza A viruses requires viral RNA synthesis and nuclear export [PDF]
, 2014 This work is supported by grants from the Wellcome Trust (grants 087751/A/08/Z) and MRC (G1001726/1).We have examined the requirements for virus transcription and replication and thus the roles of input and progeny genomes in the generation of interferon
Randall, Richard E +4 more
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Frontiers in Cell and Developmental Biology, 2022 Viruses package host RNAs in their virions which are associated with a range of functions in the viral life cycle. Previous transcriptomic profiling of host RNA packaging mostly focused on retroviruses.
Noah Peña +21 more
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Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. [PDF]
, 2014 Bluetongue virus (BTV), a member of the Orbivirus genus within the Reoviridae family, has a genome of 10 double-stranded RNA segments, with three distinct size classes.
Roy, Polly +3 more
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The NS3 protein of rice hoja blanca virus suppresses RNA silencing in mammalian cells [PDF]
, 2008 The NS3 protein of the tenuivirus rice hoja blanca virus (RHBV) has previously been shown to represent the viral RNA interference (RNAi) suppressor and is active in both plant and insect cells by binding short interfering RNAs (siRNAs) in vitro.
Hemmes, J.C. +3 more
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