Results 271 to 280 of about 1,877,035 (363)

Corrigendum: Fine-tuning p53 activity by modulating the interaction between eukaryotic translation initiation factor eIF4E and RNA-binding protein RBM38. [PDF]

Genes Dev
Sun W, Laubach K, Lucchessi C, Zhang Y, Chen M, Zhang J, Chen X.   +6 more
europepmc   +1 more source

Influence of the RNA-Binding Protein HuR in pVHL-Regulated p53 Expression in Renal Carcinoma Cells

, 2003
Stefanie Galbán, Jennifer L. Martindale, Krystyna Mazan-Mamczarz, Isabel López de Silanes, Jinshui Fan, Wengong Wang, Jochen Decker, Myriam Gorospe   +7 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

PRMT1 oligomerization regulates RNA-binding protein cascade to promote pancreatic cancer. [PDF]

Life Sci Alliance
Ru Y, Zhou X, Wang X, Sun W, He Y, Hu G, Li W, Hu D, Jiang M, Su Z, Niu F, Chen G, Zeng J, Sui SF, Liu W, Li Y, Chen S.   +16 more
europepmc   +1 more source

PolyC-Binding Protein 1 Interacts with 5′-Untranslated Region of Enterovirus 71 RNA in Membrane-Associated Complex to Facilitate Viral Replication

, 2014
Zhen Luo, Xingchen Dong, Youxing Li, Qi Zhang, Chol-Ho Kim, Yu Song, Lei Kang, Yingle Liu, Kailang Wu, Jianguo Wu   +9 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

SARS-CoV-2 RNA-binding protein suppresses extracellular miRNA release. [PDF]

RNA Biol
Mun H, Shin CH, Fei Q, Giraldo AEL, Choi KM, Lee JW, Kim K, Min KW, Shi L, Bedford MT, Kim DC, Chun YL, Ryu S, Kim D, Chang JH, Westrope RT, Shay M, Nguyen E, Hur JK, Agyenda A, Kim NC, Kang SU, Lee W, Yoon JH.   +23 more
europepmc   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

The RNA-binding protein RBM39 scaffolds an m⁶A-dependent RNA decay complex that destabilizes Tat transcripts and restricts HIV-1 reactivation. [PDF]

PLoS Biol
Deng X, Xie S, Zhou M, Yuan Q, Wu S, Huang P, Chen M, Zeng J, Guo P, Qin J, Chen C, Liu J, Liu B, He X, Sun L, Zhang H, Li L, Pan T.   +17 more
europepmc   +1 more source

RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis

Lin-Yun Chen, Liwen Wang, Jie Wen, Jinpu Cao, Rui Zhou, Jinlin Yang, Ye Xiao, Tian Su, Yan Huang, Qi Guo, Hai-Yan Zhou, Xiang‐Hang Luo, Feng Xu   +12 more
openalex   +1 more source