Results 31 to 40 of about 2,365,116 (344)
RNA‐binding properties of hnRNP proteins [PDF]
European Journal of Biochemistry, 1988 The RNA‐binding properties of the hnRNP monoparticle proteins were examined using a renaturing blotting procedure. All ‘core’ proteins are able to bind single‐stranded nucleic acids, probably not sequence‐specific. The core proteins C1 and, in one case A2 and B2, are able to bind nucleic acids which are double‐stranded or which show a high degree of ...
Schenkel, J. +3 more
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RNA-Binding Proteins in Pulmonary Hypertension [PDF]
International Journal of Molecular Sciences, 2020 Pulmonary hypertension (PH) is a life-threatening disease characterized by significant vascular remodeling and aberrant expression of genes involved in inflammation, apoptosis resistance, proliferation, and metabolism. Effective therapeutic strategies are limited, as mechanisms underlying PH pathophysiology, especially abnormal expression of genes ...
Hui Zhang +3 more
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Effective RNA Regulation by Combination of Multiple Programmable RNA-Binding Proteins
Applied Sciences, 2020 RNAs play important roles in gene expression through translation and RNA splicing. Regulation of specific RNAs is useful to understand and manipulate specific transcripts.
Misaki Sugimoto +3 more
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Autophagy, 2019 Ferroptosis is a recently discovered form of programmed cell death, but its regulatory mechanisms remain poorly understood. Here, we show that the RNA-binding protein ZFP36/TTP (ZFP36 ring finger protein) plays a crucial role in regulating ferroptosis in
Zili Zhang +10 more
semanticscholar +1 more source
Technology in Cancer Research & Treatment, 2020 RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS +4 more
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Chloroplast RNA-binding proteins [PDF]
Current Genetics, 2003 Chloroplast gene expression is regulated by nucleus-encoded factors, which mainly act at the post-transcriptional level. Plastid RNA-binding proteins (RBPs) represent good candidates for mediating these functions. The picture emerging from recent analyses is that of a great number of differentially regulated RBPs, which are organized in distinct ...
openaire +3 more sources
Biomolecules, 2020 Spatiotemporal translational regulation plays a key role in determining cell fate and function. Specifically, in neurons, local translation in dendrites is essential for synaptic plasticity and long-term memory formation.
Rie Ohashi, Nobuyuki Shiina
doaj +1 more source
RNA Binding Proteins in the miRNA Pathway [PDF]
International Journal of Molecular Sciences, 2015 microRNAs (miRNAs) are short ~22 nucleotides (nt) ribonucleic acids which post-transcriptionally regulate gene expression. miRNAs are key regulators of all cellular processes, and the correct expression of miRNAs in an organism is crucial for proper development and cellular function. As a result, the miRNA biogenesis pathway is highly regulated.
Gyorgy Hutvagner +2 more
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Nature Communications, 2023 Viral RNA-host protein interactions are indispensable during RNA virus transcription and replication, but their detailed structural and dynamical features remain largely elusive. Here, we characterize the binding interface for the SARS-CoV-2 stem-loop 3 (
Dong Zhang +7 more
doaj +1 more source
RNA-Binding Proteins in Plant Immunity [PDF]
Journal of Pathogens, 2011 Plant defence responses against pathogen infection are crucial to plant survival. The high degree of regulation of plant immunity occurs both transcriptionally and posttranscriptionally. Once transcribed, target gene RNA must be processed prior to translation. This includes polyadenylation,5′capping, editing, splicing, and mRNA export.
Shuai Huang, Virginia Woloshen, Xin Li
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