Results 41 to 50 of about 2,765,005 (400)
Characterization of a novel association between two trypanosome-specific proteins and 5S rRNA. [PDF]
PLoS ONE, 2012 P34 and P37 are two previously identified RNA binding proteins in the flagellate protozoan Trypanosoma brucei. RNA interference studies have determined that the proteins are essential and are involved in ribosome biogenesis.
Martin Ciganda, Noreen Williams
doaj +1 more source
Saturation mutagenesis reveals manifold determinants of exon definition. [PDF]
, 2017 To illuminate the extent and roles of exonic sequences in the splicing of human RNA transcripts, we conducted saturation mutagenesis of a 51-nt internal exon in a three-exon minigene.
Anquetil, Vincent +9 more
core +2 more sources
The regulatory impact of RNA-binding proteins on microRNA targeting
Nature Communications, 2021 Argonaute is the primary mediator of metazoan miRNA targeting (MT). Among the currently identified >1,500 human RNA-binding proteins (RBPs), there are only a handful of RBPs known to enhance MT and several others reported to suppress MT, leaving the ...
Sukjun Kim +14 more
semanticscholar +1 more source
RNA Binding Proteins in the miRNA Pathway [PDF]
International Journal of Molecular Sciences, 2015 microRNAs (miRNAs) are short ~22 nucleotides (nt) ribonucleic acids which post-transcriptionally regulate gene expression. miRNAs are key regulators of all cellular processes, and the correct expression of miRNAs in an organism is crucial for proper development and cellular function. As a result, the miRNA biogenesis pathway is highly regulated.
Gyorgy Hutvagner +2 more
openaire +3 more sources
Two RNA-binding proteins mediate the sorting of miR223 from mitochondria into exosomes
eLife, 2023 Fusion of multivesicular bodies (MVBs) with the plasma membrane results in the secretion of intraluminal vesicles (ILVs), or exosomes. The sorting of one exosomal cargo RNA, miR223, is facilitated by the RNA-binding protein, YBX1 (Shurtleff et al., 2016).
Liang Ma, Jasleen Singh, Randy Schekman
doaj +1 more source
Trim25 is an RNA-specific activator of Lin28a/TuT4-mediated uridylation [PDF]
, 2014 SummaryRNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4 ...
Ascano +45 more
core +3 more sources
RNA-Binding Proteins in Plant Immunity [PDF]
Journal of Pathogens, 2011 Plant defence responses against pathogen infection are crucial to plant survival. The high degree of regulation of plant immunity occurs both transcriptionally and posttranscriptionally. Once transcribed, target gene RNA must be processed prior to translation. This includes polyadenylation,5′capping, editing, splicing, and mRNA export.
Shuai Huang, Virginia Woloshen, Xin Li
openaire +2 more sources
Gadd45a is an RNA binding protein and is localized in nuclear speckles. [PDF]
PLoS ONE, 2011 The Gadd45 proteins play important roles in growth control, maintenance of genomic stability, DNA repair, and apoptosis. Recently, Gadd45 proteins have also been implicated in epigenetic gene regulation by promoting active DNA demethylation.
Yuliya A Sytnikova +4 more
doaj +1 more source
mBio, 2022 Excessive inflammation can cause tissue damage and autoimmunity, sometimes accompanied by severe morbidity or mortality. Numerous negative feedback mechanisms exist to prevent unchecked inflammation, but this restraint may come at the cost of suboptimal ...
Giraldina Trevejo-Nuñez +6 more
doaj +1 more source
Protein interactions in Xenopus germ plasm RNP particles [PDF]
, 2013 Hermes is an RNA-binding protein that we have previously reported to be found in the ribonucleoprotein (RNP) particles of Xenopus germ plasm, where it is associated with various RNAs, including that encoding the germ line determinant Nanos1.
A Anyanful +45 more
core +3 more sources