Results 51 to 60 of about 2,765,005 (400)
Advances in the characterization of RNA‐binding proteins
WIREs RNA, 2016 From transcription, to transport, storage, and translation, RNA depends on association with different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and protein mass‐spectrometry have started to unveil genome‐wide interactions of RBPs but many aspects still remain out of sight.
Domenica Marchese +5 more
openaire +5 more sources
RNA-binding proteins in neurological diseases [PDF]
Science China Life Sciences, 2014 Emerging studies support that RNA-binding proteins (RBPs) play critical roles in human biology and pathogenesis. RBPs are essential players in RNA processing and metabolism, including pre-mRNA splicing, polyadenylation, transport, surveillance, mRNA localization, mRNA stability control, translational control and editing of various types of RNAs ...
Jianghong Liu +5 more
openaire +4 more sources
FLASH: ultra-fast protocol to identify RNA-protein interactions in cells
, 2019 Determination of the in vivo binding sites of RNA-binding proteins (RBPs) is paramount to understanding their function and how they affect different aspects of gene regulation.
Akhtar, A. +4 more
core +1 more source
The increasing diversity of functions attributed to the SAFB family of RNA/DNA binding proteins [PDF]
, 2016 RNA-binding proteins play a central role in cellular metabolism by orchestrating the complex interactions of coding, structural and regulatory RNA species.
Idris, Jalilah +4 more
core +2 more sources
PLoS Biology, 2004 Genes encoding RNA-binding proteins are diverse and abundant in eukaryotic genomes. Although some have been shown to have roles in post-transcriptional regulation of the expression of specific genes, few of these proteins have been studied systematically.
A. Gerber, D. Herschlag, P. Brown
semanticscholar +1 more source
Bio-Protocol, 2021 RNA-protein interactions are often mediated by dedicated canonical RNA binding domains. However, interactions through non-canonical domains with unknown specificity are increasingly observed, raising the question how RNA targets are recognized. Knowledge
Marisa Müller +2 more
doaj +1 more source
Secondary structure prediction for RNA binding domain in RNP proteins identifies βαβ as the main structural motif [PDF]
, 1989 In eukaryotic cells transcript processing is strictly dependent upon binding of specific proteins. Nuclear RNA binding proteins share a common domain, which is involved in RNA binding.
Di Cesare, G. +3 more
core +1 more source
Nature Cell Biology, 2019 Traditionally viewed as an autodigestive pathway, autophagy also facilitates cellular secretion; however, the mechanisms underlying these processes remain unclear.
Andrew M. Leidal +16 more
semanticscholar +1 more source
RNA‐PROTACs: Degraders of RNA‐Binding Proteins
Angewandte Chemie, 2020 Defects in the functions of RNA binding proteins (RBPs) are at the origin of many diseases; however, targeting RBPs with conventional drugs has proven difficult.
Alice Ghidini +4 more
semanticscholar +1 more source
Data of protein-RNA binding sites
Data in Brief, 2017 Despite the increasing number of protein-RNA complexes in structure databases, few data resources have been made available which can be readily used in developing or testing a method for predicting either protein-binding sites in RNA sequences or RNA-binding sites in protein sequences. The problem of predicting protein-binding sites in RNA has received
Byungkyu Park +3 more
openaire +4 more sources