Results 241 to 250 of about 987,281 (377)

Construction and validation of a cell based reporter assay for identifying inhibitors of SARS coronavirus 2 RNA dependent RNA polymerase activity. [PDF]

Sci Rep
Kang E, Yoon H, Lee J, Lee J, Kim S, Jo I, Han SB, Jeong DG, Cho S.   +8 more
europepmc   +1 more source

Viroid-like RNA-dependent RNA polymerase-encoding ambiviruses are abundant in complex fungi. [PDF]

Front Microbiol, 2023
Chong LC, Lauber C.
europepmc   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

Discovery of a non-nucleoside inhibitor that binds to a novel site in the palm domain of the respiratory syncytial virus RNA-dependent RNA polymerase. [PDF]

J Virol
Kalin JH, Yin Y, Tran MT, Piassek M, Fung A, Grosse S, Jacoby E, Bhaumik A, Adhikary S, Miller R, Lemmens C, Lutter FH, Pieters S, Cooymans L, Rombouts G, Oehlrich D, Tomaso S, Lozada K, Garcia MO, Anson B, De Bruyn S, Smith-Monroy C, Neefs J-M, Conceição-Neto N, Stoops B, van Vlijmen H, Patrick A, Yu X, Wong V, Krosky D, Abeywickrema P, Mason S, Jin Z, Jonckers THM, Sharma S.   +34 more
europepmc   +1 more source

Human super antibody to viral RNA-dependent RNA polymerase produced by a modified Sortase self-cleave-bacteria surface display system. [PDF]

Microb Cell Fact, 2023
Glab-Ampai K, Mahasongkram K, Chulanetra M, Saenlom T, Thueng-In K, Sookrung N, Chaicumpa W.   +6 more
europepmc   +1 more source

Rapid Enhancement of Chick Intestinal DNA-Dependent RNA Polymerase II Activity by 1α,25-Dihydroxyvitamin D ₃ , In Vivo

, 1974
Joseph E. Zerwekh, Mark R. Haussler, Thomas J. Lindell   +2 more
openalex   +1 more source

Daunorubicin Inhibition of DNA‐Dependent RNA Polymerases from Ehrlich Ascites Tumor Cells [PDF]

, 1976
Véronique Barthelemy-Clavey, Catherine MOLINIER, Geneviève Aubel‐Sadron, R Maral   +3 more
openalex   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Developing Allosteric Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase. [PDF]

ChemMedChem
Chayka A, Danda M, Dostálková A, Spiwok V, Klimešová A, Kapisheva M, Zgarbová M, Weber J, Ruml T, Rumlová M, Janeba Z.   +10 more
europepmc   +1 more source

LGP2 directly interacts with flavivirus NS5 RNA-dependent RNA polymerase and downregulates its pre-elongation activities. [PDF]

PLoS Pathog, 2023
Tan Z, Wu J, Huang L, Wang T, Zheng Z, Zhang J, Ke X, Zhang Y, Liu Y, Wang H, Tao J, Gong P.   +11 more
europepmc   +1 more source