Results 31 to 40 of about 4,315,290 (339)

RILogo: visualizing RNA–RNA interactions [PDF]

Bioinformatics, 2012
Abstract Summary: With the increasing amount of newly discovered non-coding RNAs, the interactions between RNA molecules become an increasingly important aspect for characterizing their functionality. Many computational tools have been developed to predict the formation of duplexes between two RNAs, either based on single sequences or ...
Menzel, Karl Peter, Seemann, Ernst Stefan, Gorodkin, Jan   +2 more
openaire   +3 more sources

Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone

Bone & Joint Research, 2022
Aims: Osteoarthritis (OA) is a common degenerative joint disease. The osteocyte transcriptome is highly relevant to osteocyte biology. This study aimed to explore the osteocyte transcriptome in subchondral bone affected by OA.
Jun Zhou, Zhiyi He, Jiarui Cui, Xiaoling Liao, Hui Cao, Yo Shibata, Takashi Miyazaki, Jiaming Zhang   +7 more
doaj   +1 more source

Interaction of yeast eIF4G with spliceosome components Implications in pre-mRNA processing events [PDF]

, 2009
International audienceAs evidenced from mammalian cells the eukaryotic translation initiation factor eIF4G has a putative role in nuclear RNA metabolism. Here we investigate whether this role is conserved in the yeast Saccharomyces cerevisiae.
Barrass, J. David, Beggs, Jean D., Fromont-Racine, Micheline, Jacquier, Alain, Kafasla, Panagiota, Lewis, Joe, Thompson, Elizabeth   +6 more
core   +2 more sources

Clinical study of real-time polymerase chain reaction test kit for SARS-CoV-2 ribonucleic acids detection

Фармакоэкономика, 2022
Objective: development and validation of a reverse transcription polymerase chain reaction (RT-PCR) test kit for SARS-CoV-2 ribonucleic acids (RNA) qualitative detection adapted for using with automated station for RNA extraction.Material and methods ...
M. Yu. Dmitryukova, A. A. Golod, M. E. Senina, A. E. Gushchin   +3 more
doaj   +1 more source

Recognition of two distinct elements in the RNA substrate by the RNA-binding domain of the T. thermophilus DEAD box helicase Hera [PDF]

, 2013
DEAD box helicases catalyze the ATP-dependent destabilization of RNA duplexes. Whereas duplex separation is mediated by the helicase core shared by all members of the family, flanking domains often contribute to binding of the RNA substrate.
Klostermeier, Dagmar, Linden, Martin H., Rudolph, Markus G., Steimer, Lenz, Wurm, Jan Philip, Wöhnert, Jens   +5 more
core   +1 more source

RT-PCR detection of SARS-CoV-2 in nasopharyngeal and salivary specimens: contribution of alternative collection systems and extraction processes to cope with mass screening. Interpretation of low viral loads

Journal of Laboratory Medicine, 2022
Due to massive screening of the persistent coronavirus SARS-CoV-2, supply difficulties emerged for swabs and extraction reagents leading to test alternative choices.
Robinet Sylvain, Parisot François, Cochonot Laurie, Schiltz Benjamin, Paboeuf Camille, Nedelec Clement, Espinet Laurent, Heddebaut Alexis   +7 more
doaj   +1 more source

RNA-Binding protein HuR and the members of miR-200 family play an unconventional role in the regulation of c-Jun mRNA [PDF]

, 2016
Post-transcriptional gene regulation is a fundamental step for coordinating cellular response in a variety of processes. RNA-binding proteins (RBPs) and microRNAs (miRNAs) are the most important factors responsible for this regulation.
BOZZONI, Irene, De Vito, Francesca, DEL VECCHIO, GIORGIA, Mannironi, Cecilia, PRESUTTI, Carlo, Risi, Adele, Saunders, Sita J   +6 more
core   +1 more source

Reticulocyte RNA-Dependent RNA Polymerase [PDF]

Proceedings of the National Academy of Sciences, 1973
A cytoplasmic, microsomal bound RNA-dependent RNA polymerase has been purified 2500-fold from rabbit reticulocyte lysates. The synthesis of RNA with the purified enzyme is absolutely dependent on the addition of an RNA template. The best template is hemoglobin messenger RNA, while bacteriophage RNA and poly(A,G) are less active, and DNA is completely ...
K M, Downey, J J, Byrnes, B S, Jurmark, A G, So   +3 more
openaire   +2 more sources

Breast Cancer Prevention: Current Approaches and Future Directions

European Journal of Breast Health, 2018
The topic of breast cancer prevention is very broad. All aspects of the topic, therefore, cannot be adequately covered in a single review. The objective of this review is to discuss strategies in current use to prevent breast cancer, as well as potential
Edward R. Sauter
doaj   +1 more source

RNA Unwinding by the Trf4/Air2/Mtr4 Polyadenylation (TRAMP) Complex [PDF]

, 2012
Many RNA-processing events in the cell nucleus involve the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex, which contains the poly(A) polymerase Trf4p, the Zn-knuckle protein Air2p, and the RNA helicase Mtr4p.
Anderson, James T., Jankowsky, Eckhard, Jia, Huijue, Wang, Xuying   +3 more
core   +2 more sources