Results 251 to 260 of about 5,666,730 (325)

RNA degradation in human mitochondria: the journey is not finished. [PDF]

Hum Mol Genet
Santonoceto G, Jurkiewicz A, Szczesny RJ.   +2 more
europepmc   +1 more source

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.

Cell, 2005
J. LaCava, J. Houseley, Cosmin Saveanu, E. Petfalski, E. Thompson, A. Jacquier, D. Tollervey   +6 more
semanticscholar   +1 more source

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Correction: A dedicated diribonuclease resolves a key bottleneck for the terminal step of RNA degradation.

Elife, 2022
Kim SK, Lormand JD, Weiss CA, Eger KA, Turdiev H, Turdiev A, Winkler WC, Sondermann H, Lee VT.   +8 more
europepmc   +1 more source

Synergistic activation of Toll-like receptor 8 by two RNA degradation products

Nature Structural &Molecular Biology, 2015
M. Geyer, K. Pelka, E. Latz
semanticscholar   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Understanding the mechanism of RNA degradation in the mammalian nonsense-mediated mRNA decay pathway

, 2011
Mühlemann, Oliver, Nicholson, Pamela
core  

Optimization of FFPE preparation and identification of gene attributes associated with RNA degradation. [PDF]

NAR Genom Bioinform
Lin Y, Dong ZH, Ye TY, Yang JM, Xie M, Luo JC, Gao J, Guo AY.   +7 more
europepmc   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin. [PDF]

Elife, 2020
Shipkovenska G, Durango A, Kalocsay M, Gygi SP, Moazed D.   +4 more
europepmc   +1 more source