Results 211 to 220 of about 125,592 (278)
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Sepsis‐induced acute lung injury (ALI) remains challenging to treat, with conventional anti‐inflammatory therapies offering limited efficacy. The lymphatic system is crucial for removing edema and inflammatory mediators, and its impairment can exacerbate lung injury.
He Wang +4 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Spinocerebellar ataxia type 3 (SCA3) is a polyglutamine (polyQ) neurogenerative disorder that results from CAG trinucleotide repeat expansions in the ATXN3 gene, leading to toxic protein aggregate formation and cellular pathway dysfunction.
Tiago Moreira‐Gomes +9 more
wiley +1 more source
RNA granules associated with SAMD9-mediated poxvirus restriction are similar to antiviral granules in composition but do not require TIA1 for poxvirus restriction. [PDF]
Virology, 2019 Meng X, Xiang Y.
europepmc +1 more source
Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
PROTEOMICS, EarlyView.ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development
PROTEOMICS, EarlyView.ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia +7 more
wiley +1 more source
Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice
PROTEOMICS, EarlyView.ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min +8 more
wiley +1 more source
New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.
J Cell Sci, 2019 Das R +8 more
europepmc +1 more source
Anti‐Allergic Potential of Chamaecrista nomame and Its Compound Luteolin for Novel Asthma Therapy
Phytotherapy Research, EarlyView.Chamaecrista nomame (CN) and its active compound luteolin attenuate allergic airway inflammation by inhibiting mast cell activation and suppressing NF‐κB/MAPK signaling, leading to reduced cytokine production and OVA‐specific IgE levels. ABSTRACT Asthma is a chronic inflammatory disease driven by dysregulated immune responses and mast cell activation ...
Tae Kyeom Kang +8 more
wiley +1 more source
Small, EarlyView.A thermoresponsive complex coacervate is engineered to transport liquid‐core capsules loaded with human adipose‐derived stem cells, forming modular, hierarchically organized tissue‐forming units. This injectable platform enables precise spatial control while maintaining high cell viability, offering a versatile and bioinspired strategy for minimally ...
Luís P. G. Monteiro +5 more
wiley +1 more source
RNA Granules and Diseases: A Case Study of Stress Granules in ALS and FTLD. [PDF]
Adv Exp Med Biol, 2016 Fan AC, Leung AK.
europepmc +1 more source