Results 1 to 10 of about 125,618 (325)

RNA Helicase A Regulates the Replication of RNA Viruses [PDF]

Viruses, 2021
The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell.
Rui-Zhu Shi, Yuan-Qing Pan, Li Xing
doaj   +3 more sources

The conserved C-terminus of the PcrA/UvrD helicase interacts directly with RNA polymerase [PDF]

PLoS ONE, 2013
Copyright: © 2013 Gwynn et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
A Alzu, A Niedziela-Majka, A Urban, Abigail J. Smith, AJ Smith, AM Deaconescu, C Bruand, C Chen, Colin P. Guy, CP Guy, D Dutta, D Ursic, DB Srivastava, DE Kim, DT Jones, Emma J. Gwynn, G Shaw, GE Crooks, H Boubakri, H Jia, HE Mischo, HM Arthur, HS Subramanya, I Moszer, J Atkinson, J Atkinson, JS Finkel, JS Papadopoulos, JT Reardon, JT Yeeles, JY Lee, K Skourti-Stathaki, L Manelyte, LE Bird, LE Mechanic, LF Westblade, MA Petit, MA Petit, Maria Spies, Mark S. Dillingham, MC Hall, ME Fairman-Williams, MF Noirot-Gros, MF Noirot-Gros, MR Singleton, MS Dillingham, MS Dillingham, Nigel J. Savery, NJ Savery, NS Gilhooly, O Delumeau, O Yüce, P McGlynn, P Soultanas, P Soultanas, Peter McGlynn, R Kanagaraj, RC Centore, RR Iyer, S Iordanescu, S Korolev, SS Velankar, TM Lohman, V Epshtein, W Yang, X Veaute, Y Qi, Y Yang, Z Ni   +68 more
core   +14 more sources

Role and therapeutic potential of DEAD-box RNA helicase family in colorectal cancer. [PDF]

Front Oncol, 2023
Colorectal cancer (CRC) is the third most commonly diagnosed and the second cancer-related death worldwide, leading to more than 0.9 million deaths every year. Unfortunately, this disease is changing rapidly to a younger age, and in a more advanced stage
Zheng B, Chen X, Ling Q, Cheng Q, Ye S.
europepmc   +2 more sources

Molecular characterization of DDX26, a human DEAD-box RNA helicase, located on chromosome 7p12 [PDF]

Brazilian Journal of Medical and Biological Research, 2001
DEAD-box proteins comprise a family of ATP-dependent RNA helicases involved in several aspects of RNA metabolism. Here we report the characterization of the human DEAD-box RNA helicase DDX26. The gene is composed of 14 exons distributed over an extension
Anamaria A. Camargo, D. N. Nunes, Helena B. Samaia, L. Liu, V. Peter Collins, Andrew J.G. Simpson, Emmanuel Dias‐Neto   +6 more
openalex   +3 more sources

Genome-wide systematic survey and analysis of the RNA helicase gene family and their response to abiotic stress in sweetpotato. [PDF]

BMC Plant Biol
Sweetpotato (Ipomoea batatas (L.) Lam.) holds a crucial position as one of the staple foods globally, however, its yields are frequently impacted by environmental stresses.
Mu F, Zheng H, Zhao Q, Zhu M, Dong T, Kai L, Li Z.   +6 more
europepmc   +2 more sources

Genome-wide comparative in silico analysis of the RNA helicase gene family in Zea mays and Glycine max: a comparison with Arabidopsis and Oryza sativa. [PDF]

PLoS ONE, 2013
RNA helicases are enzymes that are thought to unwind double-stranded RNA molecules in an energy-dependent fashion through the hydrolysis of NTP. RNA helicases are associated with all processes involving RNA molecules, including nuclear transcription ...
Ruirui Xu, Shizhong Zhang, Jinguang Huang, Chengchao Zheng   +3 more
doaj   +1 more source

Dengue Virus NS4b N-Terminus Disordered Region Interacts with NS3 Helicase C-Terminal Subdomain to Enhance Helicase Activity

Viruses, 2022
Dengue virus replicates its single-stranded RNA genome in membrane-bound complexes formed on the endoplasmic reticulum, where viral non-structural proteins (NS) and RNA co-localize.
Satyamurthy Kundharapu, Tirumala Kumar Chowdary   +1 more
doaj   +1 more source

Structural basis of the T4 bacteriophage primosome assembly and primer synthesis

Nature Communications, 2023
The T4 bacteriophage gp41 helicase and gp61 primase assemble into a primosome to couple DNA unwinding with RNA primer synthesis for DNA replication. How the primosome is assembled and how the primer length is defined are unclear.
Xiang Feng, Michelle M. Spiering, Ruda de Luna Almeida Santos, Stephen J. Benkovic, Huilin Li   +4 more
doaj   +1 more source

HrpA, an RNA helicase involved in RNA processing, is required for mouse infectivity and tick transmission of the Lyme disease spirochete. [PDF]

PLoS Pathogens, 2013
The Lyme disease spirochete Borrelia burgdorferi must differentially express genes and proteins in order to survive in and transit between its tick vector and vertebrate reservoir. The putative DEAH-box RNA helicase, HrpA, has been recently identified as
Aydan Salman-Dilgimen, Pierre-Olivier Hardy, Justin D Radolf, Melissa J Caimano, George Chaconas   +4 more
doaj   +1 more source

RNA helicase domains of viral origin in proteins of insect retrotransposons: possible source for evolutionary advantages [PDF]

PeerJ, 2017
Recently, a novel phenomenon of horizontal gene transfer of helicase-encoding sequence from positive-stranded RNA viruses to LINE transposons in insect genomes was described.
Sergey Y. Morozov, Ekaterina A. Lazareva, Andrey G. Solovyev   +2 more
doaj   +2 more sources