Results 111 to 120 of about 92,282 (271)

Chromosome‐scale genome assembly of the South American fruit fly, Anastrepha fraterculus sp.1

open access: yesInsect Science, EarlyView.
Anastrepha fraterculus sp. 1 is a major fruit fly pest in Argentina, currently controlled through chemical treatments and traps. This study aims to enhance the genomic understanding of this species to support the development of sterile insect technique as well as the use of innovative technologies.
Máximo Rivarola   +15 more
wiley   +1 more source

Iflaviruses in arthropods: when small is mighty

open access: yesInsect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia   +3 more
wiley   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for WHO CNS5 adult‐type diffuse gliomas

open access: yesBrain Pathology, EarlyView.
ADAPTR recommendations for Adult‐type Diffuse Gliomas in Resource‐restrained settings. Abstract The fifth edition of the WHO classification of CNS Tumors (WHO CNS5) has revised the diagnostic and grading criteria for Adult‐type Diffuse Gliomas (ADGs) by integrating molecular parameters with histologic features.
Vani Santosh   +11 more
wiley   +1 more source

The DEAD-box RNA Helicase RH50 Is a 23S-4.5S rRNA Maturation Factor that Functionally Overlaps with the Plastid Signaling Factor GUN1 [PDF]

open access: bronze, 2017
Francesca Paieri   +8 more
openalex   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Regulation of R‐Loop Dynamics by Proteins and Long Noncoding RNAs: An Emerging Paradigm for Cancer Treatment

open access: yesCancer Science, EarlyView.
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki   +3 more
wiley   +1 more source

RNA Helicases in Microsatellite Repeat Expansion Disorders and Neurodegeneration [PDF]

open access: gold, 2022
Lydia M. Castelli   +4 more
openalex   +1 more source

A YAP/TAZ–CDC6 Axis Initiates and Maintains Malignant Transformation

open access: yesCancer Science, EarlyView.
This study demonstrates that constitutive activation of YAP or TAZ is sufficient to induce and maintain malignant transformation in fibroblasts, identifying them as essential oncogenic drivers. Transcriptomic and functional analyses revealed CDC6 as a critical downstream effector of YAP/TAZ, with elevated expression linked to tumorigenesis across ...
David Nduru   +5 more
wiley   +1 more source

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